TEAD1 and VGLL4

Number of citations of the paper that reports this interaction (PubMedID 15140898)
37

Data Source:
HPRD (in vitro)

		TEAD1	VGLL4
Description		TEA domain transcription factor 1	vestigial like family member 4
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex TEAD-1-YAP Complex	Nucleus
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Coactivator Binding DNA Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity	Transcription Coactivator Binding Protein Binding
	Biological Process	Transcription Initiation From RNA Polymerase II Promoter Hippo Signaling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Protein-containing Complex Assembly Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II	Negative Regulation Of Transcription, DNA-templated
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Central retinal vein equivalent ( 26567291) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diisocyanate-induced asthma ( 25918132) HDL cholesterol levels x loop diuretics use interaction ( 31806883) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435)	Anorexia nervosa ( 21079607) Blond vs. brown/black hair color ( 30531825) Body mass index ( 28892062) Chronic obstructive pulmonary disease ( 30804561) Clopidogrel active metabolite levels ( 28207573) Height ( 25429064 31562340) Male-pattern baldness ( 28196072) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Moderate-to-late spontaneous preterm birth ( 31194736) Offspring birth weight ( 31043758) Optic disc area ( 28073927) Relative hand skill in reading disability ( 24068947) Spontaneous preterm birth with premature rupture of membranes ( 31194736)
Interacting Genes		17 interacting genes: BORCS8-MEF2B GCAT HLA-DMB INSR MAX MEF2A MEF2C MYH7 NCOA1 SRF TBP UBTD1 VGLL1 VGLL2 VGLL4 YAP1 ZDHHC17	9 interacting genes: CDK6 DAPK1 LRRK1 LRRK2 MEF2A MEF2C MFHAS1 TEAD1 TERF2IP
Entrez ID		7003	9686
HPRD ID		01802	11672
Ensembl ID		ENSG00000187079	ENSG00000144560
Uniprot IDs		P28347 Q59EF3	A0A075B6E4 A0A0A6YYI5 G5E9M7 G5E9M9 Q14135
PDB IDs		2HZD 3KYS 4RE1 4Z8E 5NNX 6HIL 6IM5
Enriched GO Terms of Interacting Partners?
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