ZBTB7A and SP3

Number of citations of the paper that reports this interaction (PubMedID 12004059)
31

Data Source:
HPRD (in vitro)

		ZBTB7A	SP3
Description		zinc finger and BTB domain containing 7A	Sp3 transcription factor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm NuRD Complex Site Of Double-strand Break DNA-dependent Protein Kinase Complex	Nuclear Chromatin Nucleus Nucleoplasm PML Body Transcriptional Repressor Complex Protein-DNA Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Corepressor Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Activating Transcription Factor Binding Histone Acetyltransferase Binding SMAD Binding Metal Ion Binding Androgen Receptor Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Glycolytic Process Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus B Cell Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Localization To Nucleus Regulation Of Apoptotic Process Erythrocyte Maturation Fat Cell Differentiation Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Androgen Receptor Signaling Pathway Double-strand Break Repair Via Classical Nonhomologous End Joining Regulation Of Transcription Regulatory Region DNA Binding	Negative Regulation Of Transcription By RNA Polymerase II Ossification Natural Killer Cell Differentiation Trophectodermal Cell Differentiation Liver Development Embryonic Placenta Development Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II B Cell Differentiation T Cell Differentiation Megakaryocyte Differentiation Monocyte Differentiation Lung Development Granulocyte Differentiation Enucleate Erythrocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Camera-type Eye Morphogenesis Embryonic Skeletal System Development Embryonic Process Involved In Female Pregnancy Definitive Hemopoiesis
Pathways			SUMOylation of transcription factors
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 28165464) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Pulse pressure ( 30578418) Reaction time ( 29844566) Red blood cell count ( 27863252)	End-stage renal disease in Type 1 diabetics ( 24029427) Lung cancer ( 28604730) Male-pattern baldness ( 27182965) Mosquito bite size ( 28199695) Otitis media (chronic/recurrent) ( 23974705) QT interval ( 24952745) Sensation seeking ( 30718321)
Interacting Genes		19 interacting genes: AR BCL6 CRBN HOMEZ KHDRBS1 MBD3 NCOR1 NCOR2 PRKDC RELA SMAD4 SP1 SP3 SP4 UBE2I XRCC5 XRCC6 ZBTB48 ZMYND8	23 interacting genes: AKT1 E2F1 EP300 ESR1 GABPA GCH1 GRIN1 HDAC1 HDAC2 HLTF NKX3-1 PIAS1 RB1 RBBP4 RPS20 SP1 STK19 SUMO1 TP53 TP73 UBE2I VEGFA ZBTB7A
Entrez ID		51341	6670
HPRD ID		10433	03483
Ensembl ID		ENSG00000178951	ENSG00000172845
Uniprot IDs		O95365	B7ZLN9 Q02447 Q59FX5 Q86TP0
PDB IDs		2IF5 2NN2
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?