FAM53C and NCK2

  • Number of citations of the paper that reports this interaction (PubMedID 25416956)
  • 381
  • Data Source:
  • BioGRID (two hybrid)

FAM53C

NCK2

Description family with sequence similarity 53 member C NCK adaptor protein 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Response to radiotherapy in prostate cancer (toxicity, urinary frequency) ( 27515689)
  • Schizophrenia ( 25056061 30285260)
  • Addiction ( 23533358)
  • Platelet distribution width ( 27863252)
  • Systolic blood pressure in sickle cell anemia ( 24058526)
Interacting Genes 3 interacting genes: NCK2 SFN YWHAE 87 interacting genes: ABI1 ABI2 ABI3 ARHGAP32 ATN1 AXIN1 AXL BCL11A CBLB CCDC33 CD3E CHN1 CPSF6 CPSF7 DDR1 DNM1 DOCK1 DOK1 DRAP1 DVL1 EEF1G EFHC2 EFNB1 EFNB2 EFS EGFR EIF3H ERBB2 ERBB3 FAM53C FASLG FCRL2 FGFR1 FXR2 FYB1 HNRNPK HOMEZ HOXC4 ILK IRS1 KHDRBS1 KIAA1217 LCP2 LIMS1 LNX1 LRRIQ3 LZTS2 MAGEA6 MASP1 MEOX2 NCKIPSD NPHS1 NR5A1 NTRK2 PAK1 PDGFRB PIK3AP1 PKD1 PKN2 PRR20A PSMD10 PTK2 RASSF7 RBM26 REL SF3B4 SKAP2 SMARCB1 SORBS2 SOS1 SPRY2 SRPK1 SRPK2 SYNPO TCF4 TNR TRIM27 TRIM41 TRIP6 UBC VARS2 VPS37B WAS WASL WBP11 WIPF2 ZBTB7B
Entrez ID 51307 8440
HPRD ID 10785 05378
Ensembl ID ENSG00000120709 ENSG00000071051
Uniprot IDs Q9NYF3 A0A0S2Z4M6 E7ERP6 O43639
PDB IDs 1U5S 1WX6 1Z3K 2B86 2CIA 2FRW 2FRY 2JXB 4E6R
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?