CDKL3 and KASH5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CDKL3	KASH5
Description		cyclin dependent kinase like 3	KASH domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Chromosome, Telomeric Region Lateral Element Cell Nuclear Outer Membrane Integral Component Of Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Meiotic Spindle Pole
	Molecular Function	Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Protein Binding Identical Protein Binding Dynein Complex Binding
	Biological Process	Cellular Protein Modification Process Protein Phosphorylation Negative Regulation Of Axon Extension Positive Regulation Of Dendrite Morphogenesis Regulation Of Cell Cycle Dendrite Extension	Double-strand Break Repair Via Homologous Recombination Actin Filament Organization Synapsis Spermatogenesis Telomere Localization Oogenesis Spindle Assembly Spindle Localization Microtubule Cytoskeleton Organization Involved In Homologous Chromosome Segregation Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation
Pathways
Drugs
Diseases
GWAS		Eosinophil counts ( 27863252) Moderate-to-late spontaneous preterm birth ( 31194736)
Interacting Genes		18 interacting genes: APP ATG4A DNAAF6 FXR2 GGA1 GOLGA2 KASH5 KRTAP10-9 LRRK2 LZTS2 MDFI MTUS2 SNRNP70 SRPK1 TRIM27 TTF2 ZBTB14 ZBTB8A	76 interacting genes: ABHD1 ADIPOQ ATF7 BAG5 BCL2L2 BET1 CCDC87 CDC73 CDKL3 CIB3 CLDN8 CRABP2 CXCL16 CXCL9 CYBC1 EMD FAM161A FAM90A1 FATE1 FIS1 FRA10AC1 FTCD GABARAPL2 GALNT2 GOSR2 GPATCH4 GPR25 HMOX1 ITM2B JAGN1 KDM1A LARP1 LAT LENG1 LHFPL5 LMNA MALL MARCHF2 MFSD5 MMP14 MS4A1 MTX2 NRIP3 NSG1 NTAQ1 OLFM4 PDGFRA PLP2 PPP1R18 RIPPLY2 RNF146 RSRC2 RTP2 SENP2 SERP2 SGTA SHMT2 SLC30A2 SLC41A2 SLN SMCO4 STBD1 STX5 TCF25 TMEM11 TMEM14C TMEM199 TMEM41A TMPRSS4 TRAF3IP3 TSHZ3 UPK1B UPK2 VAMP1 VAMP4 ZNF250
Entrez ID		51265	147872
HPRD ID		09766	08134
Ensembl ID		ENSG00000006837	ENSG00000161609
Uniprot IDs		B4DX41 Q8IVW4	Q8N6L0
PDB IDs		3ZDU
Enriched GO Terms of Interacting Partners?
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