DELEC1 and PER2

Number of citations of the paper that reports this interaction (PubMedID 23555304)
16

Data Source:
BioGRID (two hybrid)

		DELEC1	PER2
Description		deleted in esophageal cancer 1	period circadian regulator 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleolus Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function		Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Cell Proliferation	Negative Regulation Of Transcription By RNA Polymerase II Response To Ischemia Glycogen Biosynthetic Process Gluconeogenesis Fatty Acid Metabolic Process Circadian Rhythm Response To Light Stimulus Regulation Of Vasoconstriction Lactate Biosynthetic Process Negative Regulation Of Protein Ubiquitination Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Transcription, DNA-templated Regulation Of Neurogenesis Regulation Of Insulin Secretion White Fat Cell Differentiation Regulation Of Cell Cycle Regulation Of Glutamate Uptake Involved In Transmission Of Nerve Impulse Negative Regulation Of Fat Cell Proliferation Histone H3 Deacetylation Circadian Regulation Of Translation Positive Regulation Of Cold-induced Thermogenesis Positive Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription Regulatory Region DNA Binding
Pathways			Circadian Clock
Drugs
Diseases			Familial advanced sleep phase syndrome
GWAS			Chronotype ( 26955885 30696823 27494321) Morning vs. evening chronotype ( 26955885 26835600 27494321)
Interacting Genes		30 interacting genes: ARNTL BHLHE41 CIPC CLOCK CRY1 CRY2 CSNK1E CSNK2A1 CSNK2A2 CSNK2B EZH2 FBXL15 FKBP15 GSK3B NFIL3 NONO NPAS2 NR1D2 PER1 PER2 PPP1CA PPP1CB PPP1CC PPP2CA PPP2R1A PPP2R1B PPP2R5D PPP2R5E RORB RORC	19 interacting genes: BHLHE41 BTRC CLOCK CRY1 CRY2 CSNK1D CSNK1E CSNK2B DELEC1 MDM2 PER1 PER3 RORC TIMELESS TP53 TPT1 UBE2D1 UBE2D2 UBE2D3
Entrez ID		50514	8864
HPRD ID		16068	04575
Ensembl ID		ENSG00000173077	ENSG00000132326
Uniprot IDs			O15055
PDB IDs
Enriched GO Terms of Interacting Partners?
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