P4HB and TG

Number of citations of the paper that reports this interaction (PubMedID 10636893)
9

Data Source:
BioGRID (pull down)
HPRD (in vivo)

		P4HB	TG
Description		prolyl 4-hydroxylase subunit beta	thyroglobulin
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Cytoskeleton Focal Adhesion External Side Of Plasma Membrane Procollagen-proline 4-dioxygenase Complex Lamellipodium Protein-containing Complex Endoplasmic Reticulum Chaperone Complex Melanosome Extracellular Exosome	Extracellular Region Extracellular Space
	Molecular Function	RNA Binding Protein Disulfide Isomerase Activity Actin Binding Procollagen-proline 4-dioxygenase Activity Integrin Binding Protein Binding Peptide Disulfide Oxidoreductase Activity Enzyme Binding Protein Heterodimerization Activity	Hormone Activity Identical Protein Binding
	Biological Process	Protein Folding Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Chylomicron Assembly Very-low-density Lipoprotein Particle Assembly Response To Endoplasmic Reticulum Stress Interleukin-12-mediated Signaling Pathway Interleukin-23-mediated Signaling Pathway Post-translational Protein Modification Cellular Protein Metabolic Process Cell Redox Homeostasis Positive Regulation Of Cell Adhesion Positive Regulation Of Viral Entry Into Host Cell Oxidation-reduction Process Cellular Response To Hypoxia Cellular Response To Interleukin-7 Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Thyroid Hormone Generation Signal Transduction Iodide Transport Thyroid Gland Development Regulation Of Myelination Hormone Biosynthetic Process
Pathways		Collagen biosynthesis and modifying enzymes Detoxification of Reactive Oxygen Species Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Hedgehog ligand biogenesis VLDL assembly Post-translational protein phosphorylation Chylomicron assembly Interleukin-12 signaling Interleukin-23 signaling
Drugs		Zinc Ribostamycin Copper
Diseases			Thyroid dyshormonogenesis; Dyshormogenetic goiter
GWAS			Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Bone erosion in rheumatoid arthritis ( 28512992) Graves' disease ( 23612905) Hyperthyroidism ( 30367059) Hypothyroidism ( 27182965) Medication use (thyroid preparations) ( 31015401) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Temperament ( 22832960) Thyroid stimulating hormone levels ( 30367059) Vitiligo ( 27723757)
Interacting Genes		22 interacting genes: CD1D COL10A1 COL1A1 COL1A2 CSNK2A2 EIF2S1 ERO1A ERO1B ESR1 FEZ1 HNRNPD ITGB3 LGALS9 LINC00839 P4HA2 P4HA3 PRNP PTN TG UBQLN1 VWF YWHAG	9 interacting genes: APCS ASGR1 CANX CTSD CTSL HSP90B1 HSPA5 LRP2 P4HB
Entrez ID		5034	7038
HPRD ID		07181	01782
Ensembl ID		ENSG00000185624	ENSG00000042832
Uniprot IDs		A0A024R8S5 P07237	P01266
PDB IDs		1BJX 1MEK 1X5C 2BJX 2K18 3BJ5 3UEM 4EKZ 4EL1 4JU5 6I7S
Enriched GO Terms of Interacting Partners?
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