NUMA1 and EPB41L1

Number of citations of the paper that reports this interaction (PubMedID 10594058)
21

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, two hybrid, in vivo)

		NUMA1	EPB41L1
Description		nuclear mitotic apparatus protein 1	erythrocyte membrane protein band 4.1 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Spindle Pole Cell Nucleus Nucleoplasm Chromosome Cytoplasm Centrosome Spindle Cytosol Spindle Microtubule Cell Cortex Lateral Plasma Membrane Nuclear Matrix Extrinsic Component Of Plasma Membrane Dendrite Spindle Pole Centrosome Protein-containing Complex Microtubule Plus-end Microtubule Minus-end Neuronal Cell Body Cortical Microtubule Mitotic Spindle Astral Microtubule Extracellular Exosome Mitotic Spindle Microtubule Bundle Mitotic Spindle Pole Lateral Cell Cortex Cell Cortex Region Cytoplasmic Microtubule Bundle Mitotic Spindle Midzone	Cytosol Cytoskeleton Plasma Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Microtubule Binding Protein C-terminus Binding Tubulin Binding Protein Domain Specific Binding Phosphatidylinositol Binding Protein-containing Complex Binding Microtubule Plus-end Binding Microtubule Minus-end Binding Dynein Complex Binding Disordered Domain Specific Binding	Actin Binding Structural Molecule Activity Protein Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Microtubule Bundle Formation Nucleus Organization Chromosome Segregation Positive Regulation Of BMP Signaling Pathway Astral Microtubule Organization Positive Regulation Of Microtubule Polymerization Positive Regulation Of Intracellular Transport Positive Regulation Of Keratinocyte Differentiation Cell Division Meiotic Cell Cycle Positive Regulation Of Hair Follicle Development Positive Regulation Of Chromosome Segregation Anastral Spindle Assembly Regulation Of Mitotic Spindle Organization Regulation Of Metaphase Plate Congression Positive Regulation Of Protein Localization To Spindle Pole Body Positive Regulation Of Mitotic Spindle Elongation Positive Regulation Of Protein Localization To Cell Cortex Positive Regulation Of Chromosome Separation Positive Regulation Of Spindle Assembly	Cortical Actin Cytoskeleton Organization Actomyosin Structure Organization
Pathways		Recruitment of NuMA to mitotic centrosomes Mitotic Prophase	Trafficking of AMPA receptors Neurexins and neuroligins
Drugs
Diseases
GWAS		Antibody level in response to infection ( 25758998) Microalbuminuria ( 31511532) Severe influenza A (H1N1) infection ( 26379185) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Height ( 23563607) Hip circumference ( 25673412) Keratinocyte cancer (MTAG) ( 31174203)
Interacting Genes		26 interacting genes: ABRAXAS2 ACTR1A BRAP BRCC3 CCDC57 CDK6 EPB41 EPB41L1 EPB41L2 ERG F2RL1 GMCL1 GNAI1 GPSM2 NCOA6 PIM1 RAD21 RAE1 SMC1A SUMO2 TERF1 TERF2 TERF2IP TNKS YEATS4 YWHAQ	18 interacting genes: AGAP2 APP ARHGAP1 DRD2 DRD3 GRIA1 GRIA4 HSPB1 ITPR1 NR3C1 NUMA1 POT1 SRPK2 STARD13 TERF1 YWHAB YWHAQ YWHAZ
Entrez ID		4926	2036
HPRD ID		01236	04193
Ensembl ID		ENSG00000137497	ENSG00000088367
Uniprot IDs		A0A024R5M9 Q14980 Q3SYK8 Q4LE64	A0A0C4DH22 B7Z653 Q9H4G0
PDB IDs		3RO2 5GXW 6HC2
Enriched GO Terms of Interacting Partners?
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