EPB41L1 and AGAP2

Number of citations of the paper that reports this interaction (PubMedID 11136977)
58

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		EPB41L1	AGAP2
Description		erythrocyte membrane protein band 4.1 like 1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane	Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Membrane Extracellular Exosome Flemming Body
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding	GTPase Activity GTPase Activator Activity Protein Binding ATP Binding GTP Binding Protein Kinase Binding Protein Kinase Activator Activity Phosphatidylinositol 3-kinase Regulator Activity Metal Ion Binding
	Biological Process	Cortical Actin Cytoskeleton Organization Actomyosin Structure Organization	Protein Transport Endosomal Transport Actin Cytoskeleton Organization Activation Of Protein Kinase Activity Negative Regulation Of Protein Catabolic Process Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of GTPase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of 1-phosphatidylinositol-3-kinase Activity
Pathways		Trafficking of AMPA receptors Neurexins and neuroligins	Netrin-1 signaling
Drugs
Diseases
GWAS		Height ( 23563607) Hip circumference ( 25673412) Keratinocyte cancer (MTAG) ( 31174203)	Heel bone mineral density ( 30598549) Multiple sclerosis ( 21833088)
Interacting Genes		18 interacting genes: AGAP2 APP ARHGAP1 DRD2 DRD3 GRIA1 GRIA4 HSPB1 ITPR1 NR3C1 NUMA1 POT1 SRPK2 STARD13 TERF1 YWHAB YWHAQ YWHAZ	14 interacting genes: AKT1 ARF1 CDC42 EPB41L1 GRIP1 HOMER1 HOMER2 NF2 PIK3R1 PLCG1 RAC1 RAC2 RHOA TBK1
Entrez ID		2036	116986
HPRD ID		04193	05687
Ensembl ID		ENSG00000088367	ENSG00000135439
Uniprot IDs		A0A0C4DH22 B7Z653 Q9H4G0	A0A024RB55 F8VVT9 Q99490
PDB IDs			2BMJ 2IWR 2RLO
Enriched GO Terms of Interacting Partners?
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