EPB41L1 and NUMA1

Number of citations of the paper that reports this interaction (PubMedID 10594058)
21

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, two hybrid, in vivo)

		EPB41L1	NUMA1
Description		erythrocyte membrane protein band 4.1 like 1	nuclear mitotic apparatus protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane	Golgi Membrane Spindle Pole Cell Nucleus Nucleoplasm Chromosome Cytoplasm Centrosome Spindle Cytosol Spindle Microtubule Cell Cortex Lateral Plasma Membrane Nuclear Matrix Extrinsic Component Of Plasma Membrane Dendrite Spindle Pole Centrosome Protein-containing Complex Microtubule Plus-end Microtubule Minus-end Neuronal Cell Body Cortical Microtubule Mitotic Spindle Astral Microtubule Extracellular Exosome Mitotic Spindle Microtubule Bundle Mitotic Spindle Pole Lateral Cell Cortex Cell Cortex Region Cytoplasmic Microtubule Bundle Mitotic Spindle Midzone
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding	Structural Molecule Activity Protein Binding Microtubule Binding Protein C-terminus Binding Tubulin Binding Protein Domain Specific Binding Phosphatidylinositol Binding Protein-containing Complex Binding Microtubule Plus-end Binding Microtubule Minus-end Binding Dynein Complex Binding Disordered Domain Specific Binding
	Biological Process	Cortical Actin Cytoskeleton Organization Actomyosin Structure Organization	Establishment Of Mitotic Spindle Orientation Microtubule Bundle Formation Nucleus Organization Chromosome Segregation Positive Regulation Of BMP Signaling Pathway Astral Microtubule Organization Positive Regulation Of Microtubule Polymerization Positive Regulation Of Intracellular Transport Positive Regulation Of Keratinocyte Differentiation Cell Division Meiotic Cell Cycle Positive Regulation Of Hair Follicle Development Positive Regulation Of Chromosome Segregation Anastral Spindle Assembly Regulation Of Mitotic Spindle Organization Regulation Of Metaphase Plate Congression Positive Regulation Of Protein Localization To Spindle Pole Body Positive Regulation Of Mitotic Spindle Elongation Positive Regulation Of Protein Localization To Cell Cortex Positive Regulation Of Chromosome Separation Positive Regulation Of Spindle Assembly
Pathways		Trafficking of AMPA receptors Neurexins and neuroligins	Recruitment of NuMA to mitotic centrosomes Mitotic Prophase
Drugs
Diseases
GWAS		Height ( 23563607) Hip circumference ( 25673412) Keratinocyte cancer (MTAG) ( 31174203)	Antibody level in response to infection ( 25758998) Microalbuminuria ( 31511532) Severe influenza A (H1N1) infection ( 26379185) Urinary albumin-to-creatinine ratio ( 31630189 31511532)
Interacting Genes		18 interacting genes: AGAP2 APP ARHGAP1 DRD2 DRD3 GRIA1 GRIA4 HSPB1 ITPR1 NR3C1 NUMA1 POT1 SRPK2 STARD13 TERF1 YWHAB YWHAQ YWHAZ	26 interacting genes: ABRAXAS2 ACTR1A BRAP BRCC3 CCDC57 CDK6 EPB41 EPB41L1 EPB41L2 ERG F2RL1 GMCL1 GNAI1 GPSM2 NCOA6 PIM1 RAD21 RAE1 SMC1A SUMO2 TERF1 TERF2 TERF2IP TNKS YEATS4 YWHAQ
Entrez ID		2036	4926
HPRD ID		04193	01236
Ensembl ID		ENSG00000088367	ENSG00000137497
Uniprot IDs		A0A0C4DH22 B7Z653 Q9H4G0	A0A024R5M9 Q14980 Q3SYK8 Q4LE64
PDB IDs			3RO2 5GXW 6HC2
Enriched GO Terms of Interacting Partners?
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