NT5E and LAMA1

Number of citations of the paper that reports this interaction (PubMedID 10470109)
10

Data Source:
HPRD (in vivo)

		NT5E	LAMA1
Description		5'-nucleotidase ecto	laminin subunit alpha 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Cell Surface Membrane Anchored Component Of Membrane Extracellular Exosome	Extracellular Region Basement Membrane Laminin-1 Complex Laminin-3 Complex Extracellular Space Cell-cell Junction Membrane Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Nucleotide Binding 5'-nucleotidase Activity Metal Ion Binding	Signaling Receptor Binding Extracellular Matrix Structural Constituent Protein Binding Protein C-terminus Binding Glycosphingolipid Binding
	Biological Process	Purine Nucleotide Catabolic Process AMP Catabolic Process DNA Metabolic Process Leukocyte Cell-cell Adhesion Dephosphorylation NAD Metabolic Process Adenosine Biosynthetic Process Pyrimidine Nucleoside Catabolic Process Negative Regulation Of Inflammatory Response	Morphogenesis Of An Epithelial Sheet Protein Phosphorylation Cell Adhesion Cell Surface Receptor Signaling Pathway Axon Guidance Animal Organ Morphogenesis Tissue Development Regulation Of Cell Adhesion Extracellular Matrix Organization Regulation Of Cell Migration Camera-type Eye Development Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of Embryonic Development Blood Vessel Morphogenesis Epithelial Tube Branching Involved In Lung Morphogenesis Branching Involved In Salivary Gland Morphogenesis Retinal Blood Vessel Morphogenesis
Pathways		Nicotinate metabolism Pyrimidine catabolism Purine catabolism Purinergic signaling in leishmaniasis infection	Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans L1CAM interactions MET activates PTK2 signaling
Drugs		Pentoxifylline
Diseases		Calcification of joints and arteries
GWAS		Blood metabolite levels ( 24816252) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Metabolic traits ( 21886157)	Adverse response to drug ( 30420678) Response to citalopram treatment ( 22760553) Type 2 diabetes ( 30054458 22693455 30297969)
Interacting Genes		5 interacting genes: ACTB AFF1 ATP6AP1 FN1 LAMA1	20 interacting genes: ACHE APCS APP C3 COL7A1 DAG1 FBLN2 HSPG2 ITGA1 ITGA2 ITGB1 MEP1A NID1 NT5E PLAT PLG SAA1 SAA2 TMPRSS6 UBC
Entrez ID		4907	284217
HPRD ID		00552	01033
Ensembl ID		ENSG00000135318	ENSG00000101680
Uniprot IDs		P21589 Q6NZX3	P25391
PDB IDs		4H1S 4H1Y 4H2B 4H2F 4H2G 4H2I 6HXW
Enriched GO Terms of Interacting Partners?
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