YBX1 and SRSF9

Number of citations of the paper that reports this interaction (PubMedID 12604611)
45

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo)

		YBX1	SRSF9
Description		Y-box binding protein 1	serine and arginine rich splicing factor 9
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm U12-type Spliceosomal Complex Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome CRD-mediated MRNA Stability Complex Histone Pre-mRNA 3'end Processing Complex Messenger Ribonucleoprotein Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Nuclear Speck
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Nucleic Acid Binding DNA Binding Chromatin Binding Double-stranded DNA Binding Single-stranded DNA Binding DNA-binding Transcription Factor Activity RNA Binding MRNA Binding Protein Binding MiRNA Binding GTPase Binding	RNA Binding Protein Binding Protein Domain Specific Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome In Utero Embryonic Development Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Notch Signaling Pathway Epidermis Development Regulation Of Gene Expression Negative Regulation Of Translation Positive Regulation Of Transcription By RNA Polymerase II MRNA Stabilization Embryonic Morphogenesis RNA Transport TRNA Transport Negative Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Cell Division CRD-mediated MRNA Stabilization Cellular Response To Interleukin-7 Protein Localization To Cytoplasmic Stress Granule MiRNA Transport Negative Regulation Of Cellular Senescence	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus Response To Toxic Substance MRNA 3'-end Processing Response To Alkaloid MRNA Cis Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway Noncanonical activation of NOTCH3	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Menopause (age at onset) ( 26414677)
Interacting Genes		43 interacting genes: ACTA2 AKT1 ANKRD2 APBB1 CALM1 CASP8 CSNK2A1 CTCF FBXO33 FMR1 FUS GSK3B H1-2 HABP4 HLA-C HNRNPD HNRNPK IL7R IREB2 IRF1 JAM2 LCP2 LSM3 MAPK1 MYC MYCN NFYB PCBP2 PCNA PRPF40A PURA RBBP6 RPS6KA1 RPS6KA3 SLC6A4 SMAD3 SMU1 SREK1 SRSF9 TFAP2A TP53 TRAF6 VEGFA	16 interacting genes: APP C1QBP DUSP11 FUS HABP4 HNRNPUL1 IL7R ITGB5 KHDRBS3 NOL3 RBMY1A1 SAFB SCARB1 SRPK2 TRA2B YBX1
Entrez ID		4904	8683
HPRD ID		01095	09053
Ensembl ID		ENSG00000065978	ENSG00000111786
Uniprot IDs		P67809	Q13242
PDB IDs		1H95 5YTS 5YTT 5YTV 5YTX 6A6L
Enriched GO Terms of Interacting Partners?
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