YBX1 and FBXO33

Number of citations of the paper that reports this interaction (PubMedID 16797541)
10

Data Source:
HPRD (in vivo, in vitro)

		YBX1	FBXO33
Description		Y-box binding protein 1	F-box protein 33
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm U12-type Spliceosomal Complex Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome CRD-mediated MRNA Stability Complex Histone Pre-mRNA 3'end Processing Complex Messenger Ribonucleoprotein Complex Ribonucleoprotein Complex	SCF Ubiquitin Ligase Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Nucleic Acid Binding DNA Binding Chromatin Binding Double-stranded DNA Binding Single-stranded DNA Binding DNA-binding Transcription Factor Activity RNA Binding MRNA Binding Protein Binding MiRNA Binding GTPase Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome In Utero Embryonic Development Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Notch Signaling Pathway Epidermis Development Regulation Of Gene Expression Negative Regulation Of Translation Positive Regulation Of Transcription By RNA Polymerase II MRNA Stabilization Embryonic Morphogenesis RNA Transport TRNA Transport Negative Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Cell Division CRD-mediated MRNA Stabilization Cellular Response To Interleukin-7 Protein Localization To Cytoplasmic Stress Granule MiRNA Transport Negative Regulation Of Cellular Senescence	Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway Noncanonical activation of NOTCH3
Drugs
Diseases
GWAS			Advanced glycation end-product levels ( 26915486) Metabolite levels ( 23823483) Number of sexual partners ( 30643258) Systolic blood pressure ( 30224653) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		43 interacting genes: ACTA2 AKT1 ANKRD2 APBB1 CALM1 CASP8 CSNK2A1 CTCF FBXO33 FMR1 FUS GSK3B H1-2 HABP4 HLA-C HNRNPD HNRNPK IL7R IREB2 IRF1 JAM2 LCP2 LSM3 MAPK1 MYC MYCN NFYB PCBP2 PCNA PRPF40A PURA RBBP6 RPS6KA1 RPS6KA3 SLC6A4 SMAD3 SMU1 SREK1 SRSF9 TFAP2A TP53 TRAF6 VEGFA	1 interacting genes: YBX1
Entrez ID		4904	254170
HPRD ID		01095	16441
Ensembl ID		ENSG00000065978	ENSG00000165355
Uniprot IDs		P67809	Q7Z6M2
PDB IDs		1H95 5YTS 5YTT 5YTV 5YTX 6A6L
Enriched GO Terms of Interacting Partners?
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