NFIX and JMJD6

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		NFIX	JMJD6
Description		nuclear factor I X	jumonji domain containing 6, arginine demethylase and lysine hydroxylase
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Ribonucleoprotein Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding	Transcription Coactivator Activity RNA Binding Single-stranded RNA Binding Iron Ion Binding Protein Binding Demethylase Activity Histone Demethylase Activity Histone Demethylase Activity (H3-R2 Specific) Histone Demethylase Activity (H4-R3 Specific) Oxidative RNA Demethylase Activity Signaling Receptor Activity Identical Protein Binding Peptidyl-lysine 5-dioxygenase Activity P-TEFb Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Kidney Development Sprouting Angiogenesis MRNA Processing Protein Demethylation Cell Surface Receptor Signaling Pathway Heart Development RNA Splicing Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Lung Development T Cell Differentiation In Thymus Oxidative RNA Demethylation Macrophage Activation Recognition Of Apoptotic Cell Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Splicing, Via Spliceosome Erythrocyte Development Protein Homooligomerization Retina Development In Camera-type Eye Histone H3-R2 Demethylation Histone H4-R3 Demethylation
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation	HDMs demethylate histones
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744) Body mass index ( 25673413) Clozapine-induced agranulocytosis ( 25187353) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Intelligence (MTAG) ( 29326435) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252)	Retinal arteriolar caliber ( 23776548)
Interacting Genes		7 interacting genes: JMJD6 NFIB PIR QRICH1 RFX1 SKI ZNF614	27 interacting genes: AEBP2 ANKEF1 BAG5 C17orf97 CCNL1 CENPL DIP2A FGD5 FRMD6 GNA14 H2BC11 H3C1 H4C1 HMGXB4 LARP7 NAA50 NFIX NHP2 PRPF38A PSMC1 RSPO2 SLFN12 SLU7 STAC3 TAF1A U2AF1 ZNF451
Entrez ID		4784	23210
HPRD ID		01234	05371
Ensembl ID		ENSG00000008441	ENSG00000070495
Uniprot IDs		B4DHW2 D2DXM9 Q14938	Q6NYC1
PDB IDs			3K2O 3LD8 3LDB 6BNH 6GDY 6MEV
Enriched GO Terms of Interacting Partners?
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