NFIX and SKI

Number of citations of the paper that reports this interaction (PubMedID 9380514)
15

Data Source:
BioGRID (pull down, genetic interference)
HPRD (in vitro)

		NFIX	SKI
Description		nuclear factor I X	SKI proto-oncogene
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Centrosome Nuclear Body PML Body Transcriptional Repressor Complex Protein-containing Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Binding Identical Protein Binding SMAD Binding Histone Deacetylase Inhibitor Activity Repressing Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Neural Tube Closure Lens Morphogenesis In Camera-type Eye Transcription, DNA-templated Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Anterior/posterior Axis Specification Negative Regulation Of Schwann Cell Proliferation Myotube Differentiation Olfactory Bulb Development Myelination In Peripheral Nervous System Positive Regulation Of Wnt Signaling Pathway Embryonic Limb Morphogenesis BMP Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Histone Deacetylation Negative Regulation Of Activin Receptor Signaling Pathway Somatic Stem Cell Population Maintenance Camera-type Eye Development Positive Regulation Of DNA Binding Nose Morphogenesis Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Fibroblast Proliferation Camera-type Eye Morphogenesis Skeletal Muscle Fiber Development Cell Motility Roof Of Mouth Development Retina Development In Camera-type Eye Face Morphogenesis Bone Morphogenesis SMAD Protein Signal Transduction
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation	Signaling by BMP Downregulation of SMAD2/3:SMAD4 transcriptional activity Downregulation of SMAD2/3:SMAD4 transcriptional activity
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744) Body mass index ( 25673413) Clozapine-induced agranulocytosis ( 25187353) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Intelligence (MTAG) ( 29326435) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252)	Body mass index ( 26426971) Coronary artery disease ( 29212778) Platelet distribution width ( 27863252) PR interval ( 30046033) Systolic blood pressure ( 30224653) Urate levels ( 31578528)
Interacting Genes		7 interacting genes: JMJD6 NFIB PIR QRICH1 RFX1 SKI ZNF614	20 interacting genes: AKT1 GLI2 GLI3 HIPK2 JUN MECP2 MYB NCOR1 NFIX PML SIN3A SKIL SMAD1 SMAD2 SMAD3 SMAD4 SNW1 SPI1 TGFBR1 TRIM28
Entrez ID		4784	6497
HPRD ID		01234	01271
Ensembl ID		ENSG00000008441	ENSG00000157933
Uniprot IDs		B4DHW2 D2DXM9 Q14938	P12755
PDB IDs			1MR1 1SBX 5XOD
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?