JMJD6 and STAC3

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		JMJD6	STAC3
Description		jumonji domain containing 6, arginine demethylase and lysine hydroxylase	SH3 and cysteine rich domain 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Ribonucleoprotein Complex	Nucleoplasm Cytosol Voltage-gated Calcium Channel Complex T-tubule Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Synapse
	Molecular Function	Transcription Coactivator Activity RNA Binding Single-stranded RNA Binding Iron Ion Binding Protein Binding Demethylase Activity Histone Demethylase Activity Histone Demethylase Activity (H3-R2 Specific) Histone Demethylase Activity (H4-R3 Specific) Oxidative RNA Demethylase Activity Signaling Receptor Activity Identical Protein Binding Peptidyl-lysine 5-dioxygenase Activity P-TEFb Complex Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Kidney Development Sprouting Angiogenesis MRNA Processing Protein Demethylation Cell Surface Receptor Signaling Pathway Heart Development RNA Splicing Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Lung Development T Cell Differentiation In Thymus Oxidative RNA Demethylation Macrophage Activation Recognition Of Apoptotic Cell Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Splicing, Via Spliceosome Erythrocyte Development Protein Homooligomerization Retina Development In Camera-type Eye Histone H3-R2 Demethylation Histone H4-R3 Demethylation	Skeletal Muscle Contraction Neuromuscular Synaptic Transmission Intracellular Signal Transduction Skeletal Muscle Fiber Development Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		HDMs demethylate histones
Drugs
Diseases
GWAS		Retinal arteriolar caliber ( 23776548)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 25056061 29483656)
Interacting Genes		27 interacting genes: AEBP2 ANKEF1 BAG5 C17orf97 CCNL1 CENPL DIP2A FGD5 FRMD6 GNA14 H2BC11 H3C1 H4C1 HMGXB4 LARP7 NAA50 NFIX NHP2 PRPF38A PSMC1 RSPO2 SLFN12 SLU7 STAC3 TAF1A U2AF1 ZNF451	19 interacting genes: BAZ2B C1orf35 CSNK2A1 DIP2A EAF1 EAF2 ENKD1 FAM124A FAM133A FAM90A1 JMJD6 L3MBTL2 MAB21L3 NKAPD1 NSD3 PPARA SREK1IP1 ZCCHC10 ZGPAT
Entrez ID		23210	246329
HPRD ID		05371	11606
Ensembl ID		ENSG00000070495	ENSG00000185482
Uniprot IDs		Q6NYC1	A0A024RB38 Q96MF2
PDB IDs		3K2O 3LD8 3LDB 6BNH 6GDY 6MEV	2DB6 6B29
Enriched GO Terms of Interacting Partners?
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