SEPTIN2 and SH3KBP1

Number of citations of the paper that reports this interaction (PubMedID 25472714)
15

Data Source:
BioGRID (pull down)

		SEPTIN2	SH3KBP1
Description		septin 2	SH3 domain containing kinase binding protein 1
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GO Annotations	Cellular Component	Exocyst Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Spindle Plasma Membrane Axoneme Cell Cortex Septin Ring Actin Cytoskeleton Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Photoreceptor Connecting Cilium Intercellular Bridge Perinuclear Region Of Cytoplasm Ciliary Membrane Extracellular Exosome Sperm Annulus Non-motile Cilium	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Focal Adhesion Endocytic Vesicle Cytoplasmic Vesicle Membrane Neuron Projection Synapse
	Molecular Function	GTPase Activity Protein Binding GTP Binding Cadherin Binding Molecular Adaptor Activity	Protein Binding SH3 Domain Binding
	Biological Process	Smoothened Signaling Pathway Spermatogenesis Neuron Projection Development Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis	Endocytosis Apoptotic Process Cytoskeleton Organization Actin Filament Organization Cell-cell Signaling Axon Guidance Regulation Of Cell Shape Cell Migration Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of B Cell Activation Membrane Organization
Pathways		Anchoring of the basal body to the plasma membrane	EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Reelin signalling pathway InlB-mediated entry of Listeria monocytogenes into host cell Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: COG4 CSNK2A1 DAZAP2 ESR1 JPT2 MTOR PIK3R2 PLEKHF2 RNF31 S100A4 SEPTIN5 SEPTIN6 SEPTIN9 SH3KBP1 STMN1 STX1A	44 interacting genes: ABI2 ARAP3 ARHGAP27 ASAP1 ASAP2 BCAR1 BLNK BMPR1B CAPZA1 CBL CBLB CD2 GRB2 HCK INPP5D ITSN2 MVB12A NEDD4 PAK2 PDCD6 PDCD6IP PIK3CA PIK3R1 PNMA5 PSMA3 SEPTIN2 SEPTIN6 SH3BP2 SH3GL2 SH3GL3 SH3GLB1 SH3GLB2 SHKBP1 SOS1 SPRY2 STAP1 SYNJ1 TAF6 TJP2 UBB UBC UBE2I ZBTB7B ZNF219
Entrez ID		4735	30011
HPRD ID		03297	02301
Ensembl ID		ENSG00000168385	ENSG00000147010
Uniprot IDs		A0A384N6H6 Q15019	B7Z6E8 Q5JPT6 Q96B97
PDB IDs		2QA5 2QAG 2QNR	2BZ8 2K6D 2K9G 2N64 2O2O 2YDL 5ABS
Enriched GO Terms of Interacting Partners?
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