SH3KBP1 and SH3GLB1

Number of citations of the paper that reports this interaction (PubMedID 11894096)
107

Data Source:
BioGRID (pull down)

		SH3KBP1	SH3GLB1
Description		SH3 domain containing kinase binding protein 1	SH3 domain containing GRB2 like, endophilin B1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Focal Adhesion Endocytic Vesicle Cytoplasmic Vesicle Membrane Neuron Projection Synapse	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrial Outer Membrane Cytosol Midbody Cytoplasmic Vesicle Protein-containing Complex
	Molecular Function	Protein Binding SH3 Domain Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Endocytosis Apoptotic Process Cytoskeleton Organization Actin Filament Organization Cell-cell Signaling Axon Guidance Regulation Of Cell Shape Cell Migration Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of B Cell Activation Membrane Organization	Autophagy Apoptotic Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Positive Regulation Of Protein Complex Assembly Regulation Of Protein Stability Regulation Of Cytokinesis Receptor Catabolic Process Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Autophagic Cell Death Membrane Fission Positive Regulation Of Membrane Tubulation Protein Localization To Vacuolar Membrane Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Autophagosome Assembly
Pathways		EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Reelin signalling pathway InlB-mediated entry of Listeria monocytogenes into host cell Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS
Interacting Genes		44 interacting genes: ABI2 ARAP3 ARHGAP27 ASAP1 ASAP2 BCAR1 BLNK BMPR1B CAPZA1 CBL CBLB CD2 GRB2 HCK INPP5D ITSN2 MVB12A NEDD4 PAK2 PDCD6 PDCD6IP PIK3CA PIK3R1 PNMA5 PSMA3 SEPTIN2 SEPTIN6 SH3BP2 SH3GL2 SH3GL3 SH3GLB1 SH3GLB2 SHKBP1 SOS1 SPRY2 STAP1 SYNJ1 TAF6 TJP2 UBB UBC UBE2I ZBTB7B ZNF219	26 interacting genes: ADAM15 ADAM9 AMPH APP ARHGAP17 BAX BIN1 CDKN2D CMTM5 COQ8A CSDE1 DNM2 EXOSC5 FUNDC1 GADD45A GADD45G HTATIP2 HTT MTA1 PSMA1 SH3GLB2 SH3KBP1 SYNJ1 TFIP11 TPD52L2 ZNF576
Entrez ID		30011	51100
HPRD ID		02301	15333
Ensembl ID		ENSG00000147010	ENSG00000097033
Uniprot IDs		B7Z6E8 Q5JPT6 Q96B97	A0A087WW40 A0A140VJU5 Q9Y371
PDB IDs		2BZ8 2K6D 2K9G 2N64 2O2O 2YDL 5ABS
Enriched GO Terms of Interacting Partners?
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