ASPH and TRDN

Number of citations of the paper that reports this interaction (PubMedID 9287354)
135

Data Source:
HPRD (in vitro, in vivo)

		ASPH	TRDN
Description		aspartate beta-hydroxylase	triadin
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Cortical Endoplasmic Reticulum Sarcoplasmic Reticulum Membrane	Cell Endoplasmic Reticulum Cytosol Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Junctional Membrane Complex Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen
	Molecular Function	Peptide-aspartate Beta-dioxygenase Activity Structural Molecule Activity Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Electron Transfer Activity	Signaling Receptor Binding Protein Binding Protein Binding, Bridging Ion Channel Binding
	Biological Process	Muscle Contraction Pattern Specification Process Negative Regulation Of Cell Proliferation Electron Transport Chain Regulation Of Protein Stability Ion Transmembrane Transport Limb Morphogenesis Peptidyl-aspartic Acid Hydroxylation Positive Regulation Of Proteolysis Roof Of Mouth Development Face Morphogenesis Activation Of Cysteine-type Endopeptidase Activity Regulation Of Protein Depolymerization Regulation Of Cardiac Conduction	Cellular Calcium Ion Homeostasis Muscle Contraction Response To Bacterium Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cytoplasmic Microtubule Organization Ion Transmembrane Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Heart Contraction Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Cell Membrane Potential Endoplasmic Reticulum Membrane Organization Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Cardiac Conduction
Pathways		Stimuli-sensing channels Ion homeostasis	Stimuli-sensing channels Ion homeostasis
Drugs		L-Aspartic Acid Succinic acid
Diseases
GWAS		Blood protein levels ( 30072576 29875488) BRCA1/2-negative high-risk breast cancer ( 30323354) Resting heart rate ( 28270201) Urate levels in overweight individuals ( 25811787)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Borderline personality disorder ( 28632202) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Intraocular pressure ( 30591961) Metabolite levels ( 23823483) Nickel levels ( 26025379) Night sleep phenotypes ( 27126917) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		5 interacting genes: APP FBXO7 GET3 RAB2A TRDN	7 interacting genes: ASPH CALM1 CASQ1 CASQ2 HRC RYR1 SOCS3
Entrez ID		444	10345
HPRD ID		08996	04474
Ensembl ID		ENSG00000198363	ENSG00000186439
Uniprot IDs		B4DQ07 B7ZM96 Q12797	A0A590UJV0 H9ME53 Q13061 Q8IVK2
PDB IDs		5APA 5JQY 5JTC 5JZ6 5JZ8 5JZA 5JZU 6RK9
Enriched GO Terms of Interacting Partners?
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