TRDN and ASPH

Number of citations of the paper that reports this interaction (PubMedID 9287354)
135

Data Source:
HPRD (in vitro, in vivo)

		TRDN	ASPH
Description		triadin	aspartate beta-hydroxylase
Image		No pdb structure
GO Annotations	Cellular Component	Cell Endoplasmic Reticulum Cytosol Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Junctional Membrane Complex Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Cortical Endoplasmic Reticulum Sarcoplasmic Reticulum Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Protein Binding, Bridging Ion Channel Binding	Peptide-aspartate Beta-dioxygenase Activity Structural Molecule Activity Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Electron Transfer Activity
	Biological Process	Cellular Calcium Ion Homeostasis Muscle Contraction Response To Bacterium Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cytoplasmic Microtubule Organization Ion Transmembrane Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Heart Contraction Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Cell Membrane Potential Endoplasmic Reticulum Membrane Organization Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Cardiac Conduction	Muscle Contraction Pattern Specification Process Negative Regulation Of Cell Proliferation Electron Transport Chain Regulation Of Protein Stability Ion Transmembrane Transport Limb Morphogenesis Peptidyl-aspartic Acid Hydroxylation Positive Regulation Of Proteolysis Roof Of Mouth Development Face Morphogenesis Activation Of Cysteine-type Endopeptidase Activity Regulation Of Protein Depolymerization Regulation Of Cardiac Conduction
Pathways		Stimuli-sensing channels Ion homeostasis	Stimuli-sensing channels Ion homeostasis
Drugs			L-Aspartic Acid Succinic acid
Diseases
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Borderline personality disorder ( 28632202) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Intraocular pressure ( 30591961) Metabolite levels ( 23823483) Nickel levels ( 26025379) Night sleep phenotypes ( 27126917) Post bronchodilator FEV1 ( 26634245)	Blood protein levels ( 30072576 29875488) BRCA1/2-negative high-risk breast cancer ( 30323354) Resting heart rate ( 28270201) Urate levels in overweight individuals ( 25811787)
Interacting Genes		7 interacting genes: ASPH CALM1 CASQ1 CASQ2 HRC RYR1 SOCS3	5 interacting genes: APP FBXO7 GET3 RAB2A TRDN
Entrez ID		10345	444
HPRD ID		04474	08996
Ensembl ID		ENSG00000186439	ENSG00000198363
Uniprot IDs		A0A590UJV0 H9ME53 Q13061 Q8IVK2	B4DQ07 B7ZM96 Q12797
PDB IDs			5APA 5JQY 5JTC 5JZ6 5JZ8 5JZA 5JZU 6RK9
Enriched GO Terms of Interacting Partners?
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