KRTAP5-6 and HOXA1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KRTAP5-6	HOXA1
Description		keratin associated protein 5-6	homeobox A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Nuclear Chromatin
	Molecular Function	Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Keratinization	Multicellular Organism Development Sensory Perception Of Sound Optokinetic Behavior Anatomical Structure Morphogenesis Abducens Nerve Formation Outer Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Neurocranium Morphogenesis Inner Ear Development Artery Morphogenesis Regulation Of Behavior Cognition Neuromuscular Process Artery Development Semicircular Canal Formation Cochlea Development Cochlea Morphogenesis
Pathways		Keratinization	Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases			Bosley-Salih-Alorainy syndrome and Athabascan brainstem dysgenesis syndrome
GWAS		Logical memory (delayed recall) in mild cognitive impairment ( 29274321)	Chronic venous disease ( 28374850) Macular thickness ( 30535121) Multiple sclerosis ( 31604244) Small cell lung carcinoma ( 28604730) Tonsillectomy ( 27182965 28928442)
Interacting Genes		26 interacting genes: ADAMTSL4 CATSPER1 CREB5 GLRX3 HOXA1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 MEOX2 NLK NOTCH2NLA NUFIP2 OTX1 PLSCR1 RGS20 SMCP SPRY2	62 interacting genes: ADAMTSL4 ALG13 BLZF1 CCDC33 CHIC2 CHRD DUSP22 EFEMP2 GATA1 GP9 GRN KDM1A KRT31 KRT38 KRT40 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE3E LCE4A LGALS13 LPXN MDFI MGAT5B N4BP2L2 NOTCH2NLA PBX2 PIK3R1 PKNOX1 PLSCR1 PRMT6 RBCK1 RBPMS RGS17 RGS20 SDCBP SPRY1 SUV39H1 TBC1D10C TCF3 TRAF1 TRAF2 TRAPPC6A TRIM42 TRIP6
Entrez ID		440023	3198
HPRD ID		17250	00843
Ensembl ID		ENSG00000205864	ENSG00000105991
Uniprot IDs		Q6L8G9	P49639
PDB IDs
Enriched GO Terms of Interacting Partners?
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