ABCC1 and AZGP1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ABCC1	AZGP1
Description		ATP binding cassette subfamily C member 1	alpha-2-glycoprotein 1, zinc-binding
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Membrane Basolateral Plasma Membrane Extracellular Exosome	Extracellular Region Extracellular Space Nucleus Plasma Membrane External Side Of Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	ATP Binding Organic Anion Transmembrane Transporter Activity Xenobiotic Transmembrane Transporting ATPase Activity Cobalamin-transporting ATPase Activity Glutathione S-conjugate-exporting ATPase Activity Efflux Transmembrane Transporter Activity ATPase Activity Lipid-transporting ATPase Activity Glutathione Transmembrane Transporter Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Xenobiotic Transmembrane Transporter Activity	Ribonuclease Activity Protein Binding Protein Transmembrane Transporter Activity
	Biological Process	Leukotriene Metabolic Process Cobalamin Metabolic Process Cobalamin Transport Glutathione Transmembrane Transport Response To Drug Xenobiotic Transport Phospholipid Translocation Positive Regulation Of Inflammatory Response Transmembrane Transport Cell Chemotaxis Transepithelial Transport Leukotriene Transport Sphingolipid Translocation Export Across Plasma Membrane Cellular Response To Amyloid-beta	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Retina Homeostasis Positive Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Immune Response Cell Adhesion Negative Regulation Of Cell Proliferation Transmembrane Transport Protein Transmembrane Transport RNA Phosphodiester Bond Hydrolysis
Pathways		Heme degradation Cobalamin (Cbl, vitamin B12) transport and metabolism Synthesis of Leukotrienes (LT) and Eoxins (EX) ABC-family proteins mediated transport	Miscellaneous transport and binding events
Drugs		ATP Sulfinpyrazone Biricodar dicitrate Romidepsin	N-acetyl-alpha-neuraminic acid Copper
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Estimated glomerular filtration rate ( 31152163) Ischemic stroke (undetermined subtype) ( 26708676) Multiple myeloma (survival) ( 26198393) Pelvic organ prolapse (moderate/severe) ( 26545240) Psychosis proneness (perceptual aberration scale) ( 28525603) Rate of ventricular enlargement ( 31711042) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count (basophil) ( 27863252)	Red blood cell count ( 27863252)
Interacting Genes		7 interacting genes: ATP5F1A AZGP1 CSNK2A1 NPM1 NR3C1 TNFRSF17 TRAF3	4 interacting genes: ABCC1 ITGAV NUF2 SHBG
Entrez ID		4363	563
HPRD ID		01153	01910
Ensembl ID		ENSG00000103222	ENSG00000160862
Uniprot IDs		P33527	A0A140VK00 P25311
PDB IDs		2CBZ 4C3Z	1T7V 1T7W 1T7X 1T7Y 1T7Z 1T80 1ZAG 3ES6 6R2U
Enriched GO Terms of Interacting Partners?
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