AZGP1 and NUF2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		AZGP1	NUF2
Description		alpha-2-glycoprotein 1, zinc-binding	NUF2 component of NDC80 kinetochore complex
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Plasma Membrane External Side Of Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome	Chromosome, Centromeric Region Condensed Nuclear Chromosome Kinetochore Cell Nucleoplasm Cytosol Membrane Ndc80 Complex
	Molecular Function	Ribonuclease Activity Protein Binding Protein Transmembrane Transporter Activity	Molecular_function Protein Binding Protein-containing Complex Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Retina Homeostasis Positive Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Immune Response Cell Adhesion Negative Regulation Of Cell Proliferation Transmembrane Transport Protein Transmembrane Transport RNA Phosphodiester Bond Hydrolysis	Mitotic Spindle Organization Chromosome Segregation Meiotic Chromosome Segregation Cell Division Attachment Of Mitotic Spindle Microtubules To Kinetochore Kinetochore Organization
Pathways		Miscellaneous transport and binding events	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs		N-acetyl-alpha-neuraminic acid Copper
Diseases
GWAS		Red blood cell count ( 27863252)	Asthma ( 29273806) Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168) Chronic obstructive pulmonary disease (moderate to severe) ( 24621683) Diffusing capacity of carbon monoxide ( 30694715) Height ( 28552196) Myopia ( 27182965)
Interacting Genes		4 interacting genes: ABCC1 ITGAV NUF2 SHBG	10 interacting genes: ATF3 AURKA AURKB AZGP1 CENPE CENPH DTNBP1 EXOC1 NDC80 SDCBP2
Entrez ID		563	83540
HPRD ID		01910	10817
Ensembl ID		ENSG00000160862	ENSG00000143228
Uniprot IDs		A0A140VK00 P25311	Q9BZD4
PDB IDs		1T7V 1T7W 1T7X 1T7Y 1T7Z 1T80 1ZAG 3ES6 6R2U	2VE7 3IZ0
Enriched GO Terms of Interacting Partners?
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