MMP2 and TGFB1

  • Number of citations of the paper that reports this interaction (PubMedID 10652271)
  • 531
  • Data Source:
  • HPRD (in vivo, in vitro)

MMP2

TGFB1

Description matrix metallopeptidase 2 transforming growth factor beta 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Colorectal cancer ( 27145994 24836286)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Coronary artery disease ( 29212778 28714974)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Hematuria ( 30476138)
  • Hematuria (mild) ( 30476138)
  • Hematuria (moderate to severe) ( 30476138)
  • Preterm birth (maternal effect) ( 28877031)
  • Pulse pressure ( 30578418)
  • Type 2 diabetes ( 31049640)
Interacting Genes 37 interacting genes: A2M ACAN BACE1 BCAN CCL7 CLDN1 COL18A1 COL1A1 COL6A3 COL7A1 CXCL12 DCN EPHB2 FGFR1 HAPLN1 HSP90AA1 IGFBP3 IL1B ITGAV KISS1 LCN2 LGALS3 MMP14 MMP17 MMP25 MTDH MTNR1A MTNR1B PZP SPOCK1 TGFB1 THBS1 THBS2 TIMP1 TIMP2 TIMP3 TIMP4 59 interacting genes: ACVRL1 AGR3 ANGPTL4 APP BCAS3 BGN BLID BMP2 BMP3 CCDC33 CCL3 CCL5 CCN2 COL2A1 CST6 DAXX DCN DIRAS3 DPT EIF3I ENG FCN1 FKBP1A FMOD FNTA GREB1 HOXC6 ITGAV ITGB6 ITGB8 KLK5 KLK7 KLK9 LAMTOR5 LTBP1 LTBP3 LTBP4 MEOX2 MMP2 MTA3 NSD3 PDLIM2 PRSS50 PSMC3IP PZP SCGB3A1 SDC2 SNAI1 SPARC ST14 TGFB2 TGFBR1 TGFBR2 TGFBR3 THBS1 THRSP VASN VTN YWHAE
Entrez ID 4313 7040
HPRD ID 00386 01821
Ensembl ID ENSG00000087245 ENSG00000105329
Uniprot IDs A0A024R6R4 P08253 A0A499FJK2 P01137
PDB IDs 1CK7 1CXW 1EAK 1GEN 1GXD 1HOV 1J7M 1KS0 1QIB 1RTG 3AYU 1KLA 1KLC 1KLD 3KFD 4KV5 5FFO 5VQP
Enriched GO Terms of Interacting Partners?
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