AFDN and NRXN1

  • Number of citations of the paper that reports this interaction (PubMedID 9707552)
  • 50
  • Data Source:
  • BioGRID (two hybrid)

AFDN

NRXN1

Description afadin, adherens junction formation factor neurexin 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Number of alcoholic drinks required to feel an effect (long-term average) ( 31270906)
  • Body mass index ( 28892062)
  • Chromosomal aberration frequency (chromatid type) ( 31586183)
  • Chronotype ( 30696823)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Educational attainment ( 25201988)
  • General risk tolerance (MTAG) ( 30643258)
  • Isovolumetric relaxation time ( 28394258)
  • Lateral ventricle temporal horn volume ( 31530798)
  • Longevity ( 20834067)
  • Lung cancer in ever smokers ( 28604730)
  • Metabolite levels (HVA/MHPG ratio) ( 23319000)
  • Morning person ( 30696823)
  • Personality dimensions ( 20691247)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Refractive astigmatism ( 25367360)
  • Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901)
  • Severe gingival inflammation ( 28459102)
  • Systolic blood pressure ( 30224653 30578418)
  • Temperament ( 22832960)
  • Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
  • Word spelling ( 30741946)
Interacting Genes 37 interacting genes: BCR CTNNA1 EPHA7 EPHB2 EPHB3 EPHB6 F11R HRAS JAG1 LMO2 MRAS NECTIN1 NECTIN2 NECTIN3 NECTIN4 NRXN1 NRXN2 NRXN3 PFN1 PICK1 RALGDS RAP1A RAP1GAP RAP2A RIN1 RIT1 RIT2 RRAS RRAS2 SMAD2 SORBS1 SORBS2 SSX2IP TJP1 USP9X YWHAB YWHAG 29 interacting genes: AFDN APBA1 APBA2 ATP13A2 CASK MACF1 MYO16 NLGN1 NLGN2 NLGN3 NXPH1 NXPH2 NXPH3 PDZD2 RPH3A RTN4 SDCBP2 SIPA1L1 SYT1 SYT13 SYT2 SYT4 SYT5 SYT6 SYT7 SYT9 SYTL1 SYTL2 SYTL3
Entrez ID 4301 9378
HPRD ID 01164 11858
Ensembl ID ENSG00000130396 ENSG00000179915
Uniprot IDs A8MQ02 G1UI22 J3KN01 P55196 A0A0D9SEM5 A0A0D9SEQ7 A0A1D5RMU6 E7EQN4 E7ERL8 H0Y568 H7BYC7 P58400 Q9ULB1
PDB IDs 1T2M 1XZ9 2AIN 2EXG 5A6C 3B3Q 5Z8Y
Enriched GO Terms of Interacting Partners?
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