MAP3K9 and SH3RF1

Number of citations of the paper that reports this interaction (PubMedID 14504284)
24

Data Source:
HPRD (in vitro)

		MAP3K9	SH3RF1
Description		mitogen-activated protein kinase kinase kinase 9	SH3 domain containing ring finger 1
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component	Golgi Apparatus Cytosol Lamellipodium Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity JUN Kinase Kinase Kinase Activity MAP Kinase Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity	MAP-kinase Scaffold Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Phosphorylation Apoptotic Process Activation Of JNKK Activity Activation Of JUN Kinase Activity Positive Regulation Of Apoptotic Process Protein Autophosphorylation	Neuron Migration Apoptotic Process Viral Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of JNK Cascade Protein Autoubiquitination Regulation Of CD8-positive, Alpha-beta T Cell Proliferation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs		12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one
Diseases
GWAS		Anthropometric traits (multi-trait analysis) ( 30166351) Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309)	Alzheimer disease and age of onset ( 26830138) Body fat mass ( 28552196) Body mass index ( 28552196) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Night sleep phenotypes ( 27126917) Photic sneeze reflex ( 27182965) Schizophrenia ( 30285260) Weight ( 28552196)
Interacting Genes		2 interacting genes: SH3RF1 SMURF1	19 interacting genes: ADAM15 AKT1 AKT2 HERPUD1 KCNJ1 MAP3K10 MAP3K11 MAP3K12 MAP3K9 MAP4K3 PAK2 PDCD6IP RAC1 RACGAP1 SEMA6A SIAH1 UBE2D1 UBE2D3 UBE2N
Entrez ID		4293	57630
HPRD ID		15965	15335
Ensembl ID		ENSG00000006432	ENSG00000154447
Uniprot IDs		A0A087WW79 B4DZC4 G3V347 J3KPI6 P80192 Q8NEB1	Q7Z6J0
PDB IDs		3DTC 4UY9
Enriched GO Terms of Interacting Partners?
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