MEF2C and NCOA2

  • Number of citations of the paper that reports this interaction (PubMedID 12130539)
  • 36
  • Data Source:
  • HPRD (in vivo)

MEF2C

NCOA2

Description myocyte enhancer factor 2C nuclear receptor coactivator 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Accelerometer-based physical activity measurement (average acceleration) ( 29899525)
  • Alcohol consumption ( 31358974)
  • Alcohol consumption (drinks per week) ( 30643258)
  • Alzheimer's disease ( 31473137)
  • Alzheimer's disease (late onset) ( 24162737)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention deficit hyperactivity disorder ( 29325848)
  • Bipolar disorder lithium response (categorical) or schizophrenia ( 29121268)
  • Body mass index ( 26426971)
  • Bone mineral density ( 21533022 24249740 23572186)
  • Bone mineral density (hip) ( 19801982)
  • Bone mineral density (total hip) ( 29883787)
  • Bone mineral density (Ward's triangle area) ( 27397699)
  • Chronotype ( 30696823)
  • Cognitive ability ( 29186694)
  • Cognitive ability (MTAG) ( 29186694)
  • Depression ( 29700475)
  • Femoral neck bone mineral density ( 29499414 22504420)
  • General cognitive ability ( 29844566)
  • Glomerular filtration rate in chronic kidney disease ( 26420894)
  • Height ( 20881960 25282103 25429064)
  • Household income (MTAG) ( 31844048)
  • Intelligence ( 28530673)
  • Intelligence (MTAG) ( 29326435)
  • Major depressive disorder ( 27479909)
  • Mean corpuscular hemoglobin ( 27863252)
  • Mean corpuscular volume ( 27863252)
  • Mean platelet volume ( 22139419 27863252)
  • Morning person ( 30696823)
  • Multiple sclerosis ( 31604244)
  • Number of sexual partners ( 30643258)
  • Photic sneeze reflex ( 27182965)
  • Platelet count ( 22139419 27863252)
  • Platelet distribution width ( 27863252)
  • Plateletcrit ( 27863252)
  • Red blood cell count ( 27863252)
  • Regular attendance at a religious group ( 29970889)
  • Retinal arteriolar caliber ( 23776548)
  • Retinal vascular caliber ( 21060863)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 25056061 30285260)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Tonometry ( 17903302)
  • Vascular endothelial growth factor levels ( 26910538)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for body mass index ( 28448500)
  • Cardiac Troponin-T levels ( 23247143)
  • HDL cholesterol ( 30275531)
  • HDL cholesterol levels ( 28334899)
  • Intelligence (MTAG) ( 29326435)
  • Metabolite levels ( 23823483)
  • Metabolite levels (HVA-5-HIAA Factor score) ( 23319000)
  • Multiple sclerosis ( 24076602)
  • Non-small cell lung cancer ( 23144319)
  • QT interval ( 24952745)
  • Serum alkaline phosphatase levels ( 29403010)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Subclinical trait of interstitial lung disease (basilar peel-core ratio of high attentuation areas on CT scan) ( 28521775)
Interacting Genes 30 interacting genes: ASCL1 CCNB1 CDK1 COPS5 CSNK2A1 EP300 EPAS1 GATA4 HDAC4 HDAC5 HDAC7 HDAC9 MAPK14 MAPK7 MEF2D MYOD1 MYOG NCOA2 NOTCH1 PLA2G12A SMAD2 SOX18 SP1 SPTBN1 TEAD1 TWIST2 UBE2I VGLL2 VGLL4 YWHAZ 63 interacting genes: ACTN2 AHR ANKRD11 AR ARNT BRCA1 CARM1 CCND3 CCNT1 CDK4 CREBBP CTNNB1 DDX17 DDX5 DLX2 DLX5 EID1 EP300 ESR1 ESR2 ESRRB ETV1 FOS GMEB1 H3-4 H4-16 HIF1A HNF4A JUN KIF5A KIF5B KIF5C MAGEA11 MEF2C NKX2-1 NR1I2 NR2F1 NR3C1 NR4A1 OPN1LW PIAS3 PML PPARA PPARD PPARG PPFIA1 PPFIA4 PRMT1 PSMB9 RARA RORA RXRA SLC30A9 SMARCE1 SRCAP STAT6 SUMO1 TAF9 THRB TP53 TXNRD2 VDR YWHAH
Entrez ID 4208 10499
HPRD ID 02809 09066
Ensembl ID ENSG00000081189 ENSG00000140396
Uniprot IDs A0A024RAL6 A0A024RAL7 A0A0D9SGI5 D8L7E9 Q06413 B4DPW8 Q15596
PDB IDs 1GWQ 1GWR 1M2Z 1MV9 1MVC 1MZN 1P93 1T63 1T65 1UHL 1YOK 1ZDT 1ZDU 1ZKY 2AO6 2B1V 2B1Z 2B23 2FAI 2G44 2G5O 2LDC 2P15 2P1T 2P1U 2P1V 2Q7J 2Q7L 2YJD 2ZXZ 2ZY0 3A9E 3CLD 3DZU 3DZY 3E00 3E7C 3E94 3ERD 3FUG 3GN8 3K22 3K23 3KWY 3KYT 3L0E 3L0J 3L0L 3O1D 3O1E 3OAP 3OZJ 3PCU 3PLZ 3Q95 3R5M 3UP0 3UP3 4CSJ 4DOS 4E2J 4FHH 4FHI 4IA1 4IA2 4IA3 4IA7 4IQR 4IU7 4IUI 4IV2 4IV4 4IVW 4IVY 4IW6 4IW8 4IWC 4IWF 4K4J 4K6I 4M8E 4M8H 4NIE 4NQA 4OC7 4P6W 4P6X 4PLD 4PLE 4POH 4POJ 4PP3 4PP5 4PP6 4PPP 4PPS 4PXM 4Q0A 4Q13 4QE6 4QE8 4RFW 4RMC 4RMD 4RME 4RUO 4UDC 4UDD 4WG0 4ZN7 4ZN9 4ZNH 4ZNS 4ZNT 4ZNU 4ZNV 4ZNW 4ZO1 4ZSH 5APH 5APJ 5DI7 5DID 5DIE 5DIG 5DK9 5DKB 5DKE 5DKG 5DKS 5DL4 5DLR 5DMC 5DMF 5DP0 5DRJ 5DRM 5DTV 5DU5 5DUE 5DUG 5DUH 5DVS 5DVV 5DWE 5DWG 5DWI 5DWJ 5DX3 5DXB 5DXE 5DXG 5DXK 5DXM 5DXP 5DXQ 5DXR 5DY8 5DYB 5DYD 5DZ0 5DZ1 5DZ3 5DZH 5DZI 5E0W 5E0X 5E14 5E15 5E19 5E1C 5EC9 5EGV 5EHJ 5EI1 5EIT 5G3J 5G42 5G43 5G44 5G45 5G46 5G5W 5H1E 5HYR 5I4V 5IAW 5ICK 5KCC 5KCD 5KCE 5KCF 5KCT 5KCU 5KCW 5KD9 5KR9 5KRA 5KRC 5KRF 5KRH 5KRI 5KRJ 5KRK 5KRL 5KRM 5KRO 5L11 5LGA 5LYQ 5MK4 5NFP 5NFT 5NI5 5NI7 5NI8 5NIB 5Q17 5SYZ 5T1Z 5TLD 5TLF 5TLG 5TLL 5TLM 5TLO 5TLP 5TLT 5TLU 5TLV 5TLX 5TLY 5TM1 5TM2 5TM3 5TM4 5TM5 5TM6 5TM7 5TM8 5TM9 5TML 5TMM 5TMO 5TMQ 5TMR 5TMS 5TMT 5TMU 5TMV 5TMW 5TMZ 5TN1 5TN3 5TN4 5TN5 5TN6 5TN7 5TN8 5U2D 5UAN 5VB3 5VB5 5VB6 5VB7 5VQK 5VQL 5WGQ 5WZX 5XPL 5Y1J 5Y49 5YP5 5YXB 5YXD 5YXJ 5YXL 5Z12 6CZN 6D0F 6EL6 6EL7 6EL9 6ESN 6KNU 6KNV 6KNW 6OQX 6OQY 6OR1 6R7A 6R7J 6R7K 6SJM
Enriched GO Terms of Interacting Partners?
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