Description |
nuclear receptor coactivator 2 |
peroxisome proliferator activated receptor gamma |
Image |
|
|
GO Annotations |
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
- Diethylstilbestrol
- Estradiol
- Genistein
- Methyltrienolone
- 17-METHYL-17-ALPHA-DIHYDROEQUILENIN
- 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol
- N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE
- 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL
- (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL
- 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
- 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
- 2-chloro-5-nitro-N-phenylbenzamide
- dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate
- 4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol
- 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL
- (2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID
- DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE
- 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
- 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID
- 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- tributylstannanyl
- RALOXIFENE CORE
|
- Alpha-Linolenic Acid
- Icosapent
- Troglitazone
- Mesalazine
- Valproic Acid
- Indomethacin
- Rosiglitazone
- Fenoprofen
- Nateglinide
- Sulfasalazine
- Repaglinide
- Telmisartan
- Balsalazide
- Fenofibrate
- Ibuprofen
- Glipizide
- Amiodarone
- Pioglitazone
- Mitiglinide
- Bezafibrate
- Flufenamic Acid
- Resveratrol
- Phthalic Acid
- Capric acid
- Doconexent
- Oleic Acid
- (S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid
- 2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID
- Reglixane
- Elafibranor
- T131
- CLX-0921
- (2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID
- (9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid
- 2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID
- (4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid
- (5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid
- (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid
- (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid
- (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid
- difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron
- (2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID
- 3-(5-methoxy-1H-indol-3-yl)propanoic acid
- Indeglitazar
- (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid
- 2-chloro-5-nitro-N-phenylbenzamide
- (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid
- 3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid
- 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID
- (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid
- 3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE
- Triclosan
- (2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid
- Aleglitazar
- Clinofibrate
- Lobeglitazone
- Ciglitazone
- Dexibuprofen
- Omega-3 fatty acids
- Curcumin
- Arhalofenate
|
Diseases |
|
|
GWAS |
- Cardiac Troponin-T levels ( 23247143)
- HDL cholesterol ( 30275531)
- HDL cholesterol levels ( 28334899)
- Intelligence (MTAG) ( 29326435)
- Metabolite levels ( 23823483)
- Metabolite levels (HVA-5-HIAA Factor score) ( 23319000)
- Multiple sclerosis ( 24076602)
- Non-small cell lung cancer ( 23144319)
- QT interval ( 24952745)
- Serum alkaline phosphatase levels ( 29403010)
- Spherical equivalent or myopia (age of diagnosis) ( 29808027)
- Subclinical trait of interstitial lung disease (basilar peel-core ratio of high attentuation areas on CT scan) ( 28521775)
|
- Arterial stiffness index ( 31235810)
- Body mass index ( 28892062 25673413 29273807)
- Cholesterol, total ( 25961943)
- Drug-induced liver injury ( 22968431)
- Endometrial cancer ( 30093612)
- Endometrial cancer (endometrioid histology) ( 30093612)
- Eosinophil counts ( 27863252)
- Eosinophil percentage of granulocytes ( 27863252)
- Eosinophil percentage of white cells ( 27863252)
- Fasting blood insulin ( 25631608)
- Fasting blood insulin (BMI interaction) ( 22581228)
- Fasting blood insulin adjusted for BMI ( 25625282)
- Gut microbiota (functional units) ( 27694959)
- HDL cholesterol ( 30275531)
- Heel bone mineral density ( 30598549)
- Hematocrit ( 27863252)
- Hemoglobin concentration ( 27863252)
- High density lipoprotein cholesterol levels ( 29403010)
- Hip circumference adjusted for BMI ( 25673412)
- Idiopathic osteonecrosis of the femoral head ( 31135556)
- LDL cholesterol ( 25961943)
- LDL cholesterol levels ( 30698716)
- LDL cholesterol levels in current drinkers ( 30698716)
- LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Medication use (drugs used in diabetes) ( 31015401)
- Medication use (HMG CoA reductase inhibitors) ( 31015401)
- Medication use (thyroid preparations) ( 31015401)
- Modified Stumvoll Insulin Sensitivity Index (model adjusted for BMI) ( 27416945)
- Neutrophil percentage of granulocytes ( 27863252)
- Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
- Platelet count ( 29403010)
- Potassium levels ( 29403010)
- Sexual dimorphism in anthropometric traits ( 23754948)
- Systemic lupus erythematosus ( 28714469)
- Type 2 diabetes ( 22885922 18372903 24509480 30054458 29358691 30297969 29632382 31118516 20581827 17463246 30718926 17463248 17463249 28869590)
- Type 2 diabetes (adjusted for BMI) ( 29632382)
- Waist circumference ( 31453325)
- Waist circumference variance ( 31453325)
- Waist-hip ratio ( 25673412)
- Waist-to-hip ratio adjusted for BMI ( 26426971)
- Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
- Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
- Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
- Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
|
Interacting Genes |
63 interacting genes:
ACTN2
AHR
ANKRD11
AR
ARNT
BRCA1
CARM1
CCND3
CCNT1
CDK4
CREBBP
CTNNB1
DDX17
DDX5
DLX2
DLX5
EID1
EP300
ESR1
ESR2
ESRRB
ETV1
FOS
GMEB1
H3-4
H4-16
HIF1A
HNF4A
JUN
KIF5A
KIF5B
KIF5C
MAGEA11
MEF2C
NKX2-1
NR1I2
NR2F1
NR3C1
NR4A1
OPN1LW
PIAS3
PML
PPARA
PPARD
PPARG
PPFIA1
PPFIA4
PRMT1
PSMB9
RARA
RORA
RXRA
SLC30A9
SMARCE1
SRCAP
STAT6
SUMO1
TAF9
THRB
TP53
TXNRD2
VDR
YWHAH
|
106 interacting genes:
ALOX15B
ANP32A
APP
BCAS2
BRD8
CDC34
CDK5
CEP350
CNOT1
COPS5
CREBBP
DNTTIP2
EDF1
EGFR
FABP1
FHOD1
FOXO1
GADD45B
GADD45G
GRIP1
HDAC1
HDAC3
HDAC4
HELZ2
HMGA1
IGFBP3
IKBKB
JAZF1
JMJD1C
JUN
JUND
KAT2A
KAT5
KCTD13
KIF11
KIF1A
KLF5
LMO4
LRIF1
MAFF
MAP2K1
MAPK1
MAPK8
MED1
MED24
MFHAS1
MIF4GD
MSX2
MUC1
NCOA1
NCOA2
NCOA3
NCOA4
NCOA6
NCOR1
NCOR2
NFE2L2
NFE2L3
NFKB1
NFKBIB
NR0B1
NR0B2
NR2E3
NR4A1
NR4A2
NRIP1
NSD1
PAK4
PDIA2
PHB2
PML
POU1F1
PPARGC1A
PPM1B
PRKCA
RAD54L2
RANBP9
RB1
RELA
ROBO4
RXRA
RXRB
RXRG
SERPINH1
SFPQ
SIRT1
SMARCD3
STAT6
STUB1
SVIL
SYT1
TFAP2A
TNP1
TRIM24
TRIP4
UBC
UBE2I
USP7
VDR
ZBTB20
ZBTB3
ZBTB5
ZBTB9
ZNF496
ZNHIT3
ZSCAN1
|
Entrez ID |
10499 |
5468 |
HPRD ID |
09066 |
03288 |
Ensembl ID |
ENSG00000140396
|
ENSG00000132170
|
Uniprot IDs |
B4DPW8
Q15596
|
A0A494C1F9
D2KUA6
E9PFX5
P37231
|
PDB IDs |
1GWQ
1GWR
1M2Z
1MV9
1MVC
1MZN
1P93
1T63
1T65
1UHL
1YOK
1ZDT
1ZDU
1ZKY
2AO6
2B1V
2B1Z
2B23
2FAI
2G44
2G5O
2LDC
2P15
2P1T
2P1U
2P1V
2Q7J
2Q7L
2YJD
2ZXZ
2ZY0
3A9E
3CLD
3DZU
3DZY
3E00
3E7C
3E94
3ERD
3FUG
3GN8
3K22
3K23
3KWY
3KYT
3L0E
3L0J
3L0L
3O1D
3O1E
3OAP
3OZJ
3PCU
3PLZ
3Q95
3R5M
3UP0
3UP3
4CSJ
4DOS
4E2J
4FHH
4FHI
4IA1
4IA2
4IA3
4IA7
4IQR
4IU7
4IUI
4IV2
4IV4
4IVW
4IVY
4IW6
4IW8
4IWC
4IWF
4K4J
4K6I
4M8E
4M8H
4NIE
4NQA
4OC7
4P6W
4P6X
4PLD
4PLE
4POH
4POJ
4PP3
4PP5
4PP6
4PPP
4PPS
4PXM
4Q0A
4Q13
4QE6
4QE8
4RFW
4RMC
4RMD
4RME
4RUO
4UDC
4UDD
4WG0
4ZN7
4ZN9
4ZNH
4ZNS
4ZNT
4ZNU
4ZNV
4ZNW
4ZO1
4ZSH
5APH
5APJ
5DI7
5DID
5DIE
5DIG
5DK9
5DKB
5DKE
5DKG
5DKS
5DL4
5DLR
5DMC
5DMF
5DP0
5DRJ
5DRM
5DTV
5DU5
5DUE
5DUG
5DUH
5DVS
5DVV
5DWE
5DWG
5DWI
5DWJ
5DX3
5DXB
5DXE
5DXG
5DXK
5DXM
5DXP
5DXQ
5DXR
5DY8
5DYB
5DYD
5DZ0
5DZ1
5DZ3
5DZH
5DZI
5E0W
5E0X
5E14
5E15
5E19
5E1C
5EC9
5EGV
5EHJ
5EI1
5EIT
5G3J
5G42
5G43
5G44
5G45
5G46
5G5W
5H1E
5HYR
5I4V
5IAW
5ICK
5KCC
5KCD
5KCE
5KCF
5KCT
5KCU
5KCW
5KD9
5KR9
5KRA
5KRC
5KRF
5KRH
5KRI
5KRJ
5KRK
5KRL
5KRM
5KRO
5L11
5LGA
5LYQ
5MK4
5NFP
5NFT
5NI5
5NI7
5NI8
5NIB
5Q17
5SYZ
5T1Z
5TLD
5TLF
5TLG
5TLL
5TLM
5TLO
5TLP
5TLT
5TLU
5TLV
5TLX
5TLY
5TM1
5TM2
5TM3
5TM4
5TM5
5TM6
5TM7
5TM8
5TM9
5TML
5TMM
5TMO
5TMQ
5TMR
5TMS
5TMT
5TMU
5TMV
5TMW
5TMZ
5TN1
5TN3
5TN4
5TN5
5TN6
5TN7
5TN8
5U2D
5UAN
5VB3
5VB5
5VB6
5VB7
5VQK
5VQL
5WGQ
5WZX
5XPL
5Y1J
5Y49
5YP5
5YXB
5YXD
5YXJ
5YXL
5Z12
6CZN
6D0F
6EL6
6EL7
6EL9
6ESN
6KNU
6KNV
6KNW
6OQX
6OQY
6OR1
6R7A
6R7J
6R7K
6SJM
|
1FM6
1FM9
1I7I
1K74
1KNU
1NYX
1PRG
1RDT
1WM0
1ZEO
1ZGY
2ATH
2F4B
2FVJ
2G0G
2G0H
2GTK
2HFP
2HWQ
2HWR
2I4J
2I4P
2I4Z
2OM9
2P4Y
2POB
2PRG
2Q59
2Q5P
2Q5S
2Q61
2Q6R
2Q6S
2Q8S
2QMV
2VSR
2VST
2VV0
2VV1
2VV2
2VV3
2VV4
2XKW
2YFE
2ZK0
2ZK1
2ZK2
2ZK3
2ZK4
2ZK5
2ZK6
2ZNO
2ZVT
3ADS
3ADT
3ADU
3ADV
3ADW
3ADX
3AN3
3AN4
3B0Q
3B0R
3B1M
3B3K
3BC5
3CDP
3CDS
3CS8
3CWD
3D6D
3DZU
3DZY
3E00
3ET0
3ET3
3FEJ
3FUR
3G9E
3GBK
3H0A
3HO0
3HOD
3IA6
3K8S
3KMG
3LMP
3NOA
3OSI
3OSW
3PBA
3PO9
3PRG
3QT0
3R5N
3R8A
3R8I
3S9S
3SZ1
3T03
3TY0
3U9Q
3V9T
3V9V
3V9Y
3VJH
3VJI
3VN2
3VSO
3VSP
3WJ4
3WJ5
3WMH
3X1H
3X1I
4A4V
4A4W
4CI5
4E4K
4E4Q
4EM9
4EMA
4F9M
4FGY
4HEE
4JAZ
4JL4
4L96
4L98
4O8F
4OJ4
4PRG
4PVU
4PWL
4R06
4R2U
4R6S
4XLD
4XTA
4XUH
4XUM
4Y29
4YT1
5AZV
5DSH
5DV3
5DV6
5DV8
5DVC
5DWL
5F9B
5GTN
5GTO
5GTP
5HZC
5JI0
5LSG
5TTO
5TWO
5U5L
5UGM
5WQX
5WR0
5WR1
5Y2O
5Y2T
5YCN
5YCP
5Z5S
5Z6S
6AD9
6AN1
6AUG
6AVI
6C1I
6C5Q
6C5T
6D3E
6D8X
6D94
6DBH
6DCU
6DGL
6DGO
6DGP
6DGQ
6DGR
6DH9
6DHA
6E5A
6ENQ
6F2L
6FZF
6FZG
6FZJ
6FZP
6FZY
6ICJ
6IJR
6IJS
6ILQ
6IZM
6IZN
6JQ7
6K0T
6MCZ
6MD0
6MD1
6MD2
6MD4
6MS7
6O67
6O68
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|