MECP2 and SMARCA2

  • Number of citations of the paper that reports this interaction (PubMedID 15696166)
  • 94
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, in vitro)

MECP2

SMARCA2

Description methyl-CpG binding protein 2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Asthma (childhood onset) ( 27611488)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Lead levels ( 26025379)
  • Lung function (FEV1) ( 30061609)
  • Lung function (FVC) ( 30061609)
  • Monobrow ( 27182965)
  • Neuritic plaque ( 31497858)
  • Nose size ( 27182965)
  • Parkinson's disease ( 26227905)
  • Superior frontal gyrus grey matter volume ( 25335168)
  • Systolic blood pressure ( 26969751)
Interacting Genes 20 interacting genes: DNMT1 DNMT3L GTF2B H3C15 HDAC1 HIPK2 HMGB1 LBR NCOR1 PRKACA PRPF40A PRPF40B SIN3A SKI SMARCA2 SMARCB1 SOX18 SPI1 TBL1X TBL1XR1 27 interacting genes: ACTL6A ACTL6B AR ARID1B BEND7 BRCA1 CEBPA ESR1 H3C1 HSPB1 KHDRBS1 MDM2 MDM4 MECP2 MYB MYC NR0B2 NR3C1 NR4A2 PHB PITX1 PRMT5 PRPF6 RAP1A SDCBP SIN3B SS18
Entrez ID 4204 6595
HPRD ID 02050 02483
Ensembl ID ENSG00000169057 ENSG00000080503
Uniprot IDs A0A140VKC4 D3YJ43 P51608 Q59FJ6 B1ALF6 B4DNT1 B4DSC8 F6T8Q0 F6VDE0 P51531 Q56A76 Q8N9Q1
PDB IDs 1QK9 3C2I 5BT2 6C1Y 6OGJ 6OGK 2DAT 4QY4 5DKC 5DKH 6EG2 6EG3 6HAX 6HAY 6HAZ
Enriched GO Terms of Interacting Partners?
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