MCM7 and CCDC102B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MCM7	CCDC102B
Description		minichromosome maintenance complex component 7	coiled-coil domain containing 102B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Membrane MCM Complex
	Molecular Function	DNA Binding DNA Helicase Activity DNA Replication Origin Binding Single-stranded DNA Binding Protein Binding ATP Binding Single-stranded DNA-dependent ATP-dependent 3'-5' DNA Helicase Activity	Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Double-strand Break Repair Via Break-induced Replication DNA Replication Pre-replicative Complex Assembly Involved In Nuclear Cell Cycle DNA Replication DNA Unwinding Involved In DNA Replication DNA Replication Initiation DNA Strand Elongation Involved In DNA Replication Cellular Response To DNA Damage Stimulus Cell Proliferation Regulation Of Phosphorylation Response To Drug Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Xenobiotic Stimulus
Pathways		Activation of ATR in response to replication stress Unwinding of DNA Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state
Drugs
Diseases
GWAS			Caudate activity during reward ( 28927378) Liver enzyme levels (alanine transaminase) ( 24124411) Myopic maculopathy ( 29725004) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Rostral anterior cingulate cortex volume ( 31530798)
Interacting Genes		72 interacting genes: ABI2 AK8 APP ASB8 C8orf34 CCDC102B CCND1 CCNH CDC45 CDC6 CDC7 CDK7 CDKN1B CEP68 CHEK1 COG6 CRLS1 DBF4 DNAAF6 ELOC ESCO2 FHL2 GOLGA2 H3-4 HIF1A IKBKG IKZF3 INTS6 KIFC3 LNX2 MAGEA6 MBIP MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM8 MCMBP MEOX2 MIPOL1 MNAT1 NAB2 NFKBIA ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 PLK1 PNMA1 RAD17 RB1 RBL1 RBL2 RBM8A RBPMS RINT1 RPA1 SMC1A SNTA1 SP2 SSX2IP TFIP11 TREX1 TRIM27 TRIM54 UBE3A UBQLN1 USHBP1	51 interacting genes: ABI2 AK8 ARL4A ARL4D BYSL CCDC120 CCDC33 CCHCR1 CDK18 CEP19 CEP57L1 EHHADH ENKD1 EXOC5 FAM161A FBF1 FNDC11 GEM HMG20B KIFC3 LENG1 LMO4 LNX1 MAB21L2 MAGOHB MARK1 MCM7 MOS NIF3L1 NTAQ1 NXT2 PNMA5 POP5 PPP1R18 PSMA1 RCOR3 RSPH14 RTL8A RTL8B SDCBP SFN SGF29 SLIRP SPG21 SYCE1 TPM3 TRIM27 TRIM54 ZNF20 ZNF250 ZNF572
Entrez ID		4176	79839
HPRD ID		01154	08038
Ensembl ID		ENSG00000166508	ENSG00000150636
Uniprot IDs		A0A0S2Z4A5 C6EMX8 P33993	Q68D86
PDB IDs
Enriched GO Terms of Interacting Partners?
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