MCM7 and MAGEA6

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		MCM7	MAGEA6
Description		minichromosome maintenance complex component 7	MAGE family member A6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Membrane MCM Complex	Cellular_component
	Molecular Function	DNA Binding DNA Helicase Activity DNA Replication Origin Binding Single-stranded DNA Binding Protein Binding ATP Binding Single-stranded DNA-dependent ATP-dependent 3'-5' DNA Helicase Activity	Molecular_function Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Double-strand Break Repair Via Break-induced Replication DNA Replication Pre-replicative Complex Assembly Involved In Nuclear Cell Cycle DNA Replication DNA Unwinding Involved In DNA Replication DNA Replication Initiation DNA Strand Elongation Involved In DNA Replication Cellular Response To DNA Damage Stimulus Cell Proliferation Regulation Of Phosphorylation Response To Drug Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Xenobiotic Stimulus	Biological_process
Pathways		Activation of ATR in response to replication stress Unwinding of DNA Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state
Drugs
Diseases
GWAS
Interacting Genes		72 interacting genes: ABI2 AK8 APP ASB8 C8orf34 CCDC102B CCND1 CCNH CDC45 CDC6 CDC7 CDK7 CDKN1B CEP68 CHEK1 COG6 CRLS1 DBF4 DNAAF6 ELOC ESCO2 FHL2 GOLGA2 H3-4 HIF1A IKBKG IKZF3 INTS6 KIFC3 LNX2 MAGEA6 MBIP MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM8 MCMBP MEOX2 MIPOL1 MNAT1 NAB2 NFKBIA ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 PLK1 PNMA1 RAD17 RB1 RBL1 RBL2 RBM8A RBPMS RINT1 RPA1 SMC1A SNTA1 SP2 SSX2IP TFIP11 TREX1 TRIM27 TRIM54 UBE3A UBQLN1 USHBP1	40 interacting genes: ACOT7 AKAP9 ANKRD26P1 ATP6V1G1 ATPAF2 BCL7B BET1 CCDC146 CTF1 ELMOD3 EXOC5 FAM214A FRMPD1 GFOD1 HAUS1 HLA-DRB4 IQUB KLHL38 LCORL LIN37 LSM2 MCM7 MED21 MIPOL1 MORN3 NCK2 PDE4D RASSF4 RCOR3 RPL37A S100A14 SH2D4A SNAP47 SNX4 STAMBPL1 STX5 TRIM26 TRIM28 TULP3 TXNDC9
Entrez ID		4176	4105
HPRD ID		01154	02168
Ensembl ID		ENSG00000166508	ENSG00000197172
Uniprot IDs		A0A0S2Z4A5 C6EMX8 P33993	P43360
PDB IDs
Enriched GO Terms of Interacting Partners?
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