MCM2 and MCPH1

  • Number of citations of the paper that reports this interaction (PubMedID 19525936)
  • 77

MCM2

MCPH1

Description minichromosome maintenance complex component 2 microcephalin 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Alcoholic chronic pancreatitis ( 28754779)
  • Birth weight ( 31043758)
  • Carotid intima media thickness ( 30510157)
  • Cytomegalovirus antibody response ( 21993531)
  • Diastolic blood pressure ( 30224653)
  • Epirubicin-induced leukopenia ( 21799462)
  • Estimated glomerular filtration rate ( 31152163)
  • Heel bone mineral density ( 30598549)
  • Intraocular pressure ( 29785010)
  • Metabolite levels ( 23823483)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Venlafaxine response in generalised anxiety disorder (remitters vs non-remitters after 24 weeks) ( 28437668)
Interacting Genes 55 interacting genes: AKAP8 APP ATM ATR CCNB2 CCNC CDC45 CDC6 CDC7 CDK2 CDK4 CDK6 CDKN2A CDT1 CPSF1 CSNK2A1 DBF4 ELL EP300 ESCO2 FBXO7 GINS4 GNB5 GTF2B GTF2H1 H3-4 KAT7 MCM10 MCM3 MCM4 MCM5 MCM6 MCM7 MCPH1 MOB4 MPP3 ORC1 ORC2 ORC4 ORC5 ORC6 P2RX4 PHB PHC2 PLK1 RAD52 RPA1 RPA2 RPA3 RPS4X SIK1 TBP TCEA2 TERF1 TERF2IP 68 interacting genes: ABCC2 ACTG1 AKIP1 AKR7A2 ATM ATR B3GALT6 CCDC77 CCT5 CHEK1 COL1A1 COL27A1 COPB2 COPS3 CTSL DNAJA3 DNAJC19 EIF3F EIF4A2 EMG1 ENO1 FBLN1 FLNA GABARAPL2 HNRNPA2B1 HSPD1 KAT5 KDM1A LAMTOR5 LGALS3 MCM2 MCM5 MITD1 MRPL46 MT2A NCCRP1 NMI NR2F1 OBSL1 PHF11 PMVK POLD1 POLR2G PPA1 PPRC1 RACK1 RBM39 RSL24D1 RUVBL2 S100A16 SMARCB1 SMARCC2 SMOX SUPT6H TADA2A TAF1D THAP11 TPT1 TRAP1 TSEN54 UXT VIM WDR53 WDR61 WDR73 WDR75 WNT10B ZMIZ2
Entrez ID 4171 79648
HPRD ID 00303 06174
Ensembl ID ENSG00000073111 ENSG00000147316
Uniprot IDs P49736 Q8NEM0
PDB IDs 4UUZ 5BNV 5BNX 5BO0 5C3I 5JA4 2WT8 3KTF 3PA6 3SHT 3SHV 3SZM 3T1N 3U3Z
Enriched GO Terms of Interacting Partners?
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