MCM2 and CDC6

  • Number of citations of the paper that reports this interaction (PubMedID 15232106)
  • 123
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)
  • HPRD (in vitro)

MCM2

CDC6

Description minichromosome maintenance complex component 2 cell division cycle 6
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes 55 interacting genes: AKAP8 APP ATM ATR CCNB2 CCNC CDC45 CDC6 CDC7 CDK2 CDK4 CDK6 CDKN2A CDT1 CPSF1 CSNK2A1 DBF4 ELL EP300 ESCO2 FBXO7 GINS4 GNB5 GTF2B GTF2H1 H3-4 KAT7 MCM10 MCM3 MCM4 MCM5 MCM6 MCM7 MCPH1 MOB4 MPP3 ORC1 ORC2 ORC4 ORC5 ORC6 P2RX4 PHB PHC2 PLK1 RAD52 RPA1 RPA2 RPA3 RPS4X SIK1 TBP TCEA2 TERF1 TERF2IP 38 interacting genes: AKAP8L ATM ATRIP B3GALNT1 CCNA2 CCNB1 CCNE1 CCNF CDC14A CDC20 CDK1 CDK2 CDK4 CDK6 CDKN1A CDKN2A CDT1 FZR1 KAT7 MCM10 MCM2 MCM3 MCM7 MYC ORC1 ORC2 ORC3 ORC5 ORC6 PCNA PPP2R3A PPP2R3B PSKH1 RPS27A SQSTM1 TERF1 UBE2K UBR1
Entrez ID 4171 990
HPRD ID 00303 04022
Ensembl ID ENSG00000073111 ENSG00000094804
Uniprot IDs P49736 A0A024R1S2 Q99741
PDB IDs 4UUZ 5BNV 5BNX 5BO0 5C3I 5JA4 2CCH 2CCI 4I5L 4I5N
Enriched GO Terms of Interacting Partners?
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