MCPH1 and TSEN54

  • Number of citations of the paper that reports this interaction (PubMedID 29150431)
  • 3
  • Data Source:
  • BioGRID (two hybrid)

MCPH1

TSEN54

Description microcephalin 1 tRNA splicing endonuclease subunit 54
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcoholic chronic pancreatitis ( 28754779)
  • Birth weight ( 31043758)
  • Carotid intima media thickness ( 30510157)
  • Cytomegalovirus antibody response ( 21993531)
  • Diastolic blood pressure ( 30224653)
  • Epirubicin-induced leukopenia ( 21799462)
  • Estimated glomerular filtration rate ( 31152163)
  • Heel bone mineral density ( 30598549)
  • Intraocular pressure ( 29785010)
  • Metabolite levels ( 23823483)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Venlafaxine response in generalised anxiety disorder (remitters vs non-remitters after 24 weeks) ( 28437668)
  • FEV1 ( 30804560)
  • Lung function (FEV1) ( 28166213)
  • Lung function (FEV1/FVC) ( 30804560)
  • Lung function (FVC) ( 30804560)
  • Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011)
  • Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011)
  • Sight-threatening diabetic retinopathy in type 2 diabetes ( 26188370)
Interacting Genes 68 interacting genes: ABCC2 ACTG1 AKIP1 AKR7A2 ATM ATR B3GALT6 CCDC77 CCT5 CHEK1 COL1A1 COL27A1 COPB2 COPS3 CTSL DNAJA3 DNAJC19 EIF3F EIF4A2 EMG1 ENO1 FBLN1 FLNA GABARAPL2 HNRNPA2B1 HSPD1 KAT5 KDM1A LAMTOR5 LGALS3 MCM2 MCM5 MITD1 MRPL46 MT2A NCCRP1 NMI NR2F1 OBSL1 PHF11 PMVK POLD1 POLR2G PPA1 PPRC1 RACK1 RBM39 RSL24D1 RUVBL2 S100A16 SMARCB1 SMARCC2 SMOX SUPT6H TADA2A TAF1D THAP11 TPT1 TRAP1 TSEN54 UXT VIM WDR53 WDR61 WDR73 WDR75 WNT10B ZMIZ2 4 interacting genes: BRCA1 CSNK2B MCPH1 TSEN2
Entrez ID 79648 283989
HPRD ID 06174 12291
Ensembl ID ENSG00000147316 ENSG00000182173
Uniprot IDs Q8NEM0 Q7Z6J9
PDB IDs 2WT8 3KTF 3PA6 3SHT 3SHV 3SZM 3T1N 3U3Z
Enriched GO Terms of Interacting Partners?
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