MAGEA4 and AMOT

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology)

		MAGEA4	AMOT
Description		MAGE family member A4	angiomotin
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GO Annotations	Cellular Component	Cellular_component	Ruffle Nucleoplasm Cytosol Actin Filament Plasma Membrane Bicellular Tight Junction COP9 Signalosome External Side Of Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Cytoplasmic Vesicle
	Molecular Function	Molecular_function Protein Binding	Protein Binding Signaling Receptor Activity Angiostatin Binding
	Biological Process	Biological_process	Angiogenesis Vasculogenesis In Utero Embryonic Development Gastrulation With Mouth Forming Second Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Chemotaxis Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Regulation Of Cell Migration Negative Regulation Of GTPase Activity Cellular Protein Localization Hippo Signaling Positive Regulation Of Embryonic Development Cell Migration Involved In Gastrulation Blood Vessel Endothelial Cell Migration Regulation Of Small GTPase Mediated Signal Transduction
Pathways
Drugs
Diseases
GWAS
Interacting Genes		17 interacting genes: AMOT AMOTL2 APP ARNT2 BEX2 GTF3C1 HLA-A POT1 PSMD10 RAD18 TEKT4 TIGD5 TK1 TRIM69 UBXN6 UQCRB WBP2	21 interacting genes: ACTA1 APP C1orf216 KRT15 KRT31 LATS2 LMO4 LURAP1 MAGEA4 MAGI1 MAPK3 MED4 NEDD4 NEDD4L NTAQ1 PIN1 PLG PTPA SEPTIN1 SNAPC5 UNC119
Entrez ID		4103	154796
HPRD ID		02167	02327
Ensembl ID		ENSG00000147381	ENSG00000126016
Uniprot IDs		A0A024RC12 P43358	Q4VCS5
PDB IDs		1I4F 2WA0	6JJX
Enriched GO Terms of Interacting Partners?
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