SMAD9 and RANBP9

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
HPRD (two hybrid)

		SMAD9	RANBP9
Description		SMAD family member 9	RAN binding protein 9
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GO Annotations	Cellular Component	Nuclear Chromatin Intracellular Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol SMAD Protein Complex	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transforming Growth Factor Beta Receptor, Pathway-specific Cytoplasmic Mediator Activity Metal Ion Binding	Protein Binding Ran GTPase Binding Enzyme Binding
	Biological Process	Transforming Growth Factor Beta Receptor Signaling Pathway BMP Signaling Pathway SMAD Protein Signal Transduction Cellular Response To BMP Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus	MAPK Cascade Microtubule Nucleation Axon Guidance Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade
Pathways		Signaling by BMP	L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Heel bone mineral density ( 30598549 28869591) Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407) Spontaneous preterm birth (preterm birth) ( 25599974) Total body bone mineral density ( 29304378)	Breast cancer ( 29059683 23535729)
Interacting Genes		117 interacting genes: ABTB1 ACTB ACVR1 AFF1 AP2A1 ARHGAP9 ARID1B ARNT ASB2 ASH2L BAZ1A BTG2 CAMSAP1 CEP135 CHPF CLPB CPXM2 CSH1 CSH2 CTR9 CXXC5 CYP11A1 DIAPH3 DKK1 DNAJA3 DNAJC7 DST DSTN E4F1 EIF3C EIF3E EIF3F ERVV-1 EVC2 EXPH5 FLI1 FN1 FTL GRN HEY1 HEYL HUWE1 KDM1A KDM6A KMT2D LEMD3 LMO4 LNPEP LRP5 MACO1 MAN1A2 MAN1C1 MAN2B1 MBD1 MCM3AP METAP1 MGAT1 MTMR10 MTMR11 NAGK OTUB1 PABPC4 PAPPA PELP1 PHKA2 PIR PKP2 PLEC PNPLA2 PPARD PPP2R5E PRMT6 PSAP PSMD8 QARS1 RANBP9 RFX1 RMND5A RNF123 RRBP1 RUBCN SECISBP2 SF3B1 SIL1 SMAD2 SMAD3 SMAD4 SMG1 SNRNP70 SPTBN1 STAG1 SVEP1 TBCD TERF1 TINAGL1 TOB1 TRIM29 TRIP12 TTC37 TWNK UBA6 UBE3A UBQLN1 UBQLN4 UNC45A VCPIP1 VPS8 XAB2 YWHAQ ZEB2 ZNF484 ZNF557 ZNF587 ZNF587B ZNF592 ZNF83 ZSCAN4	56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MKLN1 MPHOSPH8 NCOA6 NCOR2 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 YPEL5
Entrez ID		4093	10048
HPRD ID		04484	04835
Ensembl ID		ENSG00000120693	ENSG00000010017
Uniprot IDs		A0A024RDR3 O15198	A0A024QZW3 Q96S59
PDB IDs		6FZT	5JI7 5JI9 5JIU
Enriched GO Terms of Interacting Partners?
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