SMAD9 and AFF1

  • Number of citations of the paper that reports this interaction (PubMedID 15231748)
  • 85
  • Data Source:
  • HPRD (two hybrid)

SMAD9

AFF1

Description SMAD family member 9 AF4/FMR2 family member 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery disease ( 29212778)
  • Heel bone mineral density ( 30598549 28869591)
  • Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407)
  • Spontaneous preterm birth (preterm birth) ( 25599974)
  • Total body bone mineral density ( 29304378)
  • Alzheimer's disease (cognitive decline) ( 23535033)
  • Basophil percentage of granulocytes ( 27863252)
  • Basophil percentage of white cells ( 27863252)
  • Bulimia nervosa ( 23568457)
  • Diastolic blood pressure ( 28234671)
  • Eyebrow thickness ( 26926045)
  • HDL cholesterol levels ( 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Heel bone mineral density ( 30598549 28869591)
  • Hematocrit ( 29403010 27863252)
  • Hemoglobin ( 29403010)
  • Hemoglobin concentration ( 27863252)
  • Mean corpuscular hemoglobin ( 29403010 27863252)
  • Mean corpuscular volume ( 29403010 27863252)
  • Mean platelet volume ( 27863252)
  • Medication use (thyroid preparations) ( 31015401)
  • Metabolic syndrome ( 31589552)
  • Multiple sclerosis ( 31604244)
  • Red blood cell count ( 27863252)
  • Systemic lupus erythematosus ( 22291604)
  • Total bilirubin levels ( 29403010)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
  • Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
  • Triglycerides ( 20864672 30275531 25961943 20686565)
  • White blood cell count (basophil) ( 29403010 27863252)
Interacting Genes 117 interacting genes: ABTB1 ACTB ACVR1 AFF1 AP2A1 ARHGAP9 ARID1B ARNT ASB2 ASH2L BAZ1A BTG2 CAMSAP1 CEP135 CHPF CLPB CPXM2 CSH1 CSH2 CTR9 CXXC5 CYP11A1 DIAPH3 DKK1 DNAJA3 DNAJC7 DST DSTN E4F1 EIF3C EIF3E EIF3F ERVV-1 EVC2 EXPH5 FLI1 FN1 FTL GRN HEY1 HEYL HUWE1 KDM1A KDM6A KMT2D LEMD3 LMO4 LNPEP LRP5 MACO1 MAN1A2 MAN1C1 MAN2B1 MBD1 MCM3AP METAP1 MGAT1 MTMR10 MTMR11 NAGK OTUB1 PABPC4 PAPPA PELP1 PHKA2 PIR PKP2 PLEC PNPLA2 PPARD PPP2R5E PRMT6 PSAP PSMD8 QARS1 RANBP9 RFX1 RMND5A RNF123 RRBP1 RUBCN SECISBP2 SF3B1 SIL1 SMAD2 SMAD3 SMAD4 SMG1 SNRNP70 SPTBN1 STAG1 SVEP1 TBCD TERF1 TINAGL1 TOB1 TRIM29 TRIP12 TTC37 TWNK UBA6 UBE3A UBQLN1 UBQLN4 UNC45A VCPIP1 VPS8 XAB2 YWHAQ ZEB2 ZNF484 ZNF557 ZNF587 ZNF587B ZNF592 ZNF83 ZSCAN4 9 interacting genes: H3-4 MLLT1 MLLT3 NT5E SASH1 SIAH1 SIAH2 SMAD9 TBCA
Entrez ID 4093 4299
HPRD ID 04484 08871
Ensembl ID ENSG00000120693 ENSG00000172493
Uniprot IDs A0A024RDR3 O15198 B4DJU9 P51825 Q14C88
PDB IDs 6FZT 2LM0
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?