SMAD2 and RARB

  • Number of citations of the paper that reports this interaction (PubMedID 15231748)
  • 85

SMAD2

RARB

Description SMAD family member 2 retinoic acid receptor beta
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery disease in type 1 diabetes ( 29695241)
  • Lung cancer in ever smokers ( 28604730)
  • Menarche (age at onset) ( 27182965)
  • Adventurousness ( 30643258)
  • Airflow obstruction ( 22837378)
  • Airway responsiveness in chronic obstructive pulmonary disease ( 25514360)
  • Asthma ( 29273806)
  • Blood urea nitrogen levels ( 31152163)
  • BMI (adjusted for smoking behaviour) ( 28443625)
  • BMI in smokers ( 28443625)
  • Body mass index ( 28892062 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Body mass index in physically active individuals ( 28448500)
  • Body mass index in physically inactive individuals ( 28448500)
  • Calcium levels ( 25972035)
  • Carotid intima media thickness in rheumatoid arthritis ( 30251476)
  • Chronic obstructive pulmonary disease ( 28166215 30804561)
  • Chronotype ( 30696823)
  • Coffee consumption ( 31046077)
  • Dental caries (decayed and filled deciduous teeth) ( 31533690)
  • Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690)
  • Dentures ( 31235808)
  • Dietary macronutrient intake ( 29988085)
  • FEV1 ( 30804560)
  • General risk tolerance (MTAG) ( 30643258)
  • Glaucoma (primary open-angle) ( 29891935)
  • Gout ( 22179738)
  • Heel bone mineral density ( 30598549 28869591)
  • Intraocular pressure ( 29785010 31959993)
  • Low susceptibility to hepatitis C infection ( 31206233)
  • Lung function (FEV1/FVC) ( 30804560)
  • Lung function (FVC) ( 30804560)
  • Macular thickness ( 30535121)
  • Midgestational cytokine/chemokine levels (maternal genetic effect) ( 30134952)
  • Molybdenum levels ( 26025379)
  • Mood instability ( 31168069)
  • Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
  • Obesity (extreme) ( 19553259)
  • Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070)
  • Optic disc area ( 25631615 31798171 28073927)
  • Optic disc size ( 31809533)
  • Optic nerve head parameters (multi-trait analysis) ( 31798171)
  • Peak expiratory flow ( 30804560)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Pulmonary function ( 21946350)
  • Pulmonary function (smoking interaction) ( 23284291)
  • Pursuit maintenance gain ( 29064472)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Urinary sodium excretion ( 31409800)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes 209 interacting genes: ABTB1 ACVR1B AFDN AKT1 ANAPC10 ANAPC2 ANK3 ANP32B ANP32E ANTXR2 AP1B1 ARFGAP3 ARHGEF6 ARL4D ATP5ME AXIN1 BAZ1A BECN1 BPTF BRCA1 BTBD2 C22orf46 CAMK2A CAMK2G CDC16 CDC27 CDC40 CDK2 CDK4 CDK8 CDK9 CISH COPS5 CREBBP CSH1 CSH2 CSNK1D CTNNB1 CUL5 CYP11A1 DAB2 DCAF6 DCUN1D1 DENND2B DNAJC7 DOCK8 DVL1 DYNC1H1 E2F4 EEF1A1 EID2 EIF3L ELAC2 EP300 ERBIN ESR1 ESR2 FAM161B FBN2 FHL2 FHL3 FOXG1 FOXH1 FOXO3 GATAD2B GFER GLI3 GRIPAP1 GSC GTF2I HDAC1 HDAC2 HGS HIPK2 HNF4A HOXA13 HOXA9 HOXD13 HUWE1 HYAL2 INSR IRAK2 ITCH JUN KAT2B KHDRBS1 KPNB1 LAMA5 LATS2 LCK LEF1 LEMD3 LHX9 LITAF LMO2 MAPK1 MAPK3 MAPK8 MAPK9 MECOM MED15 MED6 MEF2A MEF2C MYC MYOCD NAGK NCOA6 NEDD4L NEDD9 NEFM NFIA NFYC NOTCH4 NUAK2 NUP153 NUP214 OS9 OTUB1 PAK1 PAPOLA PAPPA PARD3 PAXIP1 PEX19 PIAS3 PIAS4 PIK3CA PLIN3 POU2AF1 PPM1A PPP2R1A PRKAR1A PSAP PSG9 PSMD11 PSMD8 PTMS RAB34 RAB38 RAN RANBP6 RANBP9 RARB RASD2 RASL12 RBL1 RHEBL1 RHOA RHOD RHOJ RIT1 RNF123 RNPC3 ROCK1 RPS14 RPS27A RUNX2 RXRA SKI SKIL SKOR2 SMAD1 SMAD3 SMAD4 SMAD7 SMAD9 SMURF1 SMURF2 SNAPIN SNIP1 SNRNP70 SNW1 SOD1 SP1 SQSTM1 SRI ST13 STAG1 STAMBP STAMBPL1 STRAP STUB1 SYT1 TBC1D1 TGFBR1 TGFBRAP1 TGIF1 TGM2 TNNT1 TOB1 TP53 TP73 TRIM62 TSC2 TUBA1B UBA52 UBR5 UCHL5 USP9X WASHC4 YY1 ZEB1 ZEB2 ZFYVE9 ZMYND11 ZNF41 ZNF8 ZNHIT6 20 interacting genes: ARID1A CCNH CEBPA CEBPB GATA3 HR MAP6 MEOX2 NCOA1 NCOA3 NCOR2 PNRC1 PRKD2 PSMC5 RXRA RXRB RXRG SMAD2 SMARCD3 SMARCE1
Entrez ID 4087 5915
HPRD ID 03221 07183
Ensembl ID ENSG00000175387 ENSG00000077092
Uniprot IDs B7Z5N5 Q15796 Q53XR6 F1D8S6 P10826 Q3SB16 Q5QHG3 Q86UC5
PDB IDs 1DEV 1KHX 1U7V 2LB3 5XOD 5ZOJ 6H3R 1HRA 1XAP 4DM6 4DM8 4JYG 4JYH 4JYI 5UAN 6SSQ
Enriched GO Terms of Interacting Partners?
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