MIRLET7I and ELAVL1

Number of citations of the paper that reports this interaction (PubMedID 24326307)
126

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		MIRLET7I	ELAVL1
Description		microRNA let-7i	ELAV like RNA binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Cytoplasmic Stress Granule Membrane Postsynapse Glutamatergic Synapse Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Complex Binding Core Promoter Sequence-specific DNA Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding Double-stranded RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding AU-rich Element Binding Protein Kinase Binding MiRNA Binding MRNA 3'-UTR AU-rich Region Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Gene Expression Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Defense Response To Protozoan Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Transcription By RNA Polymerase II	MRNA Splicing, Via Spliceosome Protein Import Into Nucleus Regulation Of MRNA Stability Positive Regulation Of Translation MRNA Stabilization Protein Homooligomerization Negative Regulation Of Gene Silencing By MiRNA 3'-UTR-mediated MRNA Stabilization Regulation Of Stem Cell Population Maintenance
Pathways			HuR (ELAVL1) binds and stabilizes mRNA mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Blood protein levels ( 28240269)
Interacting Genes		2 interacting genes: AGO2 ELAVL1	37 interacting genes: ANP32A ANP32B APOE C12orf75 CARM1 CELF2 CHEK2 CTNNB1 ERG FAF2 GJB3 HNRNPK HOTAIR IL7R KPNA1 KPNB1 MIRLET7B MIRLET7I NOS3 PAIP2 PLAU PLAUR PRKCA PRKCD PRKCE PSEN2 PTBP2 PTGS2 RBFOX2 SDCBP SET SREK1 TNPO1 TNPO2 VCP VEGFA XIAP
Entrez ID		406891	1994
HPRD ID			16025
Ensembl ID		ENSG00000199179	ENSG00000066044
Uniprot IDs			Q15717
PDB IDs			3HI9 4ED5 4EGL 4FXV 5SZW 6G2K 6GC5 6GD1 6GD2 6GD3
Enriched GO Terms of Interacting Partners?
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