ELAVL1 and FAF2

Number of citations of the paper that reports this interaction (PubMedID 23618873)
27

Data Source:
BioGRID (pull down)

		ELAVL1	FAF2
Description		ELAV like RNA binding protein 1	Fas associated factor family member 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Cytoplasmic Stress Granule Membrane Postsynapse Glutamatergic Synapse Ribonucleoprotein Complex	Extracellular Region Endoplasmic Reticulum Lipid Droplet VCP-NPL4-UFD1 AAA ATPase Complex Azurophil Granule Lumen
	Molecular Function	RNA Binding Double-stranded RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding AU-rich Element Binding Protein Kinase Binding MiRNA Binding MRNA 3'-UTR AU-rich Region Binding Protein Homodimerization Activity	Protein Binding Ubiquitin Protein Ligase Binding Lipase Binding Ubiquitin Binding Lipase Inhibitor Activity
	Biological Process	MRNA Splicing, Via Spliceosome Protein Import Into Nucleus Regulation Of MRNA Stability Positive Regulation Of Translation MRNA Stabilization Protein Homooligomerization Negative Regulation Of Gene Silencing By MiRNA 3'-UTR-mediated MRNA Stabilization Regulation Of Stem Cell Population Maintenance	Response To Unfolded Protein Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Lipid Droplet Organization Negative Regulation Of Catalytic Activity Neutrophil Degranulation
Pathways		HuR (ELAVL1) binds and stabilizes mRNA mRNA Splicing - Major Pathway	Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269)
Interacting Genes		37 interacting genes: ANP32A ANP32B APOE C12orf75 CARM1 CELF2 CHEK2 CTNNB1 ERG FAF2 GJB3 HNRNPK HOTAIR IL7R KPNA1 KPNB1 MIRLET7B MIRLET7I NOS3 PAIP2 PLAU PLAUR PRKCA PRKCD PRKCE PSEN2 PTBP2 PTGS2 RBFOX2 SDCBP SET SREK1 TNPO1 TNPO2 VCP VEGFA XIAP	11 interacting genes: ELAVL1 FAF1 FAS MAP3K1 PNPLA2 PSMD2 SMURF1 STC2 UBE2D1 UBE3A VCP
Entrez ID		1994	23197
HPRD ID		16025	16870
Ensembl ID		ENSG00000066044	ENSG00000113194
Uniprot IDs		Q15717	Q96CS3
PDB IDs		3HI9 4ED5 4EGL 4FXV 5SZW 6G2K 6GC5 6GD1 6GD2 6GD3	2DAM
Enriched GO Terms of Interacting Partners?
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