LASP1 and RHOXF2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LASP1	RHOXF2
Description		LIM and SH3 protein 1	Rhox homeobox family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Focal Adhesion Cortical Actin Cytoskeleton	Nuclear Chromatin Nucleus
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding Ion Transmembrane Transporter Activity Cadherin Binding Metal Ion Binding Actin Filament Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding
	Biological Process	Ion Transport Positive Regulation Of Signal Transduction Ion Transmembrane Transport	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression
Pathways
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)
Interacting Genes		40 interacting genes: ACD ACTA1 ACTB ACTC1 ARHGEF15 ATXN1 CDK7 COPS5 CRK DAZAP2 DNMT1 EHMT2 FHL3 FXR2 GOLGA2 KRTAP4-2 LZTS2 MDFI PLSCR1 POT1 PRKAR2B PRKG1 PRKG2 PSMA3 RBPMS REL RHOXF2 SEPTIN3 SPRY2 STAT3 TCF4 TERF1 THAP1 TINF2 TRIM27 TRIP13 UHRF1 ZBTB9 ZC2HC1A ZYX	58 interacting genes: ARID5A ARMCX2 ATN1 ATXN1 CCDC33 CCNK CHAC1 CLASRP CLDN7 CRYBA1 DAB1 DAZAP2 DEDD2 DTX2 DVL2 EFEMP2 EWSR1 FBF1 HNRNPLL HOXC13 KRTAP19-5 KRTAP19-7 LASP1 LENG8 LSM4 LZTS2 MAGED1 MED7 MVP NANOG NEU4 PITX1 PLOD3 POLR3D POU2AF1 PSMF1 RADIL RAMAC RBFOX1 RBFOX2 RBM11 RBPMS SERF2 SNAPC1 SUMO1 TENT5B TENT5C TENT5D TLE5 TMCC2 TOLLIP TRIP13 UBE2I UPF1 UTP6 VAC14 VPS25 ZBTB32
Entrez ID		3927	84528
HPRD ID		04229	02345
Ensembl ID		ENSG00000002834	ENSG00000131721
Uniprot IDs		A0A024R1S8 B4DIC4 Q14847	Q9BQY4
PDB IDs		3I35
Enriched GO Terms of Interacting Partners?
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