LAMB3 and LAMC2

Number of citations of the paper that reports this interaction (PubMedID 10964684)
2

Data Source:
HPRD (in vivo)

		LAMB3	LAMC2
Description		laminin subunit beta 3	laminin subunit gamma 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Laminin-5 Complex Laminin Complex Collagen-containing Extracellular Matrix	Extracellular Region Basement Membrane Laminin-2 Complex Extracellular Space Cell Cortex Membrane Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix
	Molecular Function	Integrin Binding Structural Molecule Activity Extracellular Matrix Structural Constituent Protein Binding	Extracellular Matrix Structural Constituent Heparin Binding
	Biological Process	Epidermis Development Animal Organ Morphogenesis Tissue Development Cell Migration Extracellular Matrix Organization Hemidesmosome Assembly Substrate Adhesion-dependent Cell Spreading Endodermal Cell Differentiation Brown Fat Cell Differentiation Basement Membrane Assembly	Cell Adhesion Motor Neuron Axon Guidance Positive Regulation Of Cell Proliferation Epidermis Development Animal Organ Morphogenesis Tissue Development Dendrite Development Extracellular Matrix Organization Positive Regulation Of Cell Migration Hemidesmosome Assembly
Pathways		Degradation of the extracellular matrix Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Anchoring fibril formation Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions Type I hemidesmosome assembly MET activates PTK2 signaling	Degradation of the extracellular matrix Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Anchoring fibril formation Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions Type I hemidesmosome assembly MET activates PTK2 signaling
Drugs
Diseases		Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)	Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS		Fentanyl consumption in laparoscopic-assisted colectomy (first 24 hours) ( 26566055)	Acne (severe) ( 30542056) Blood protein levels ( 30072576 29875488) Clozapine-induced agranulocytosis ( 25187353) HDL cholesterol ( 21347282) Morning person ( 30696823) Systemic lupus erythematosus ( 21408207)
Interacting Genes		6 interacting genes: BMP1 COL7A1 LAMA3 LAMC2 MDFI THBS1	8 interacting genes: BMP1 COL7A1 CSF1R FBLN2 LAMB3 NID1 SCAP SLA2
Entrez ID		3914	3918
HPRD ID		01032	01031
Ensembl ID		ENSG00000196878	ENSG00000058085
Uniprot IDs		A0A0S2Z3R6 Q13751	Q13753
PDB IDs
Enriched GO Terms of Interacting Partners?
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