LAMB2 and ATXN7

Number of citations of the paper that reports this interaction (PubMedID 21078624)
23

Data Source:
BioGRID (two hybrid)

		LAMB2	ATXN7
Description		laminin subunit beta 2	ataxin 7
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-3 Complex Endoplasmic Reticulum Lumen Neuromuscular Junction Synaptic Cleft Laminin Complex Laminin-11 Complex Collagen-containing Extracellular Matrix Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytosol Microtubule Cytoskeleton Nuclear Matrix
	Molecular Function	Integrin Binding Structural Molecule Activity Extracellular Matrix Structural Constituent	Protein Binding
	Biological Process	Axon Guidance Neuromuscular Junction Development Visual Perception Animal Organ Morphogenesis Tissue Development Astrocyte Development Schwann Cell Development Cell Migration Extracellular Matrix Organization Substrate Adhesion-dependent Cell Spreading Post-translational Protein Modification Cellular Protein Metabolic Process Axon Extension Involved In Regeneration Retina Development In Camera-type Eye Basement Membrane Assembly Metanephric Glomerular Visceral Epithelial Cell Development Metanephric Glomerular Basement Membrane Development	Microtubule Cytoskeleton Organization Nucleus Organization Negative Regulation Of Microtubule Depolymerization Visual Perception Histone Deubiquitination Protein Deubiquitination
Pathways		Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) MET activates PTK2 signaling Post-translational protein phosphorylation	HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases		Pierson syndrome	Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Mood instability ( 31168069) Resting heart rate ( 27798624) Ulcerative colitis ( 28067908)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 31152163) Schizophrenia ( 28991256 25056061 29483656) Type 2 diabetes ( 30054458)
Interacting Genes		8 interacting genes: ATXN7 KPNA2 ORC5 PIK3R2 PLEKHA5 RBL1 STAT3 ZNF512B	60 interacting genes: ACTN1 ACTN2 ACTN4 ADAM33 AGRN CARD10 CEP70 CEP72 COG6 CRIM1 CRX EFEMP1 EFEMP2 FBN1 FN1 GOLGA2 GOLGA3 GPRASP1 GRN IMPDH2 ITPRID2 JAG2 KALRN KAT2A LAMB1 LAMB2 LRSAM1 LTBP4 MATN2 MEGF6 MPRIP NELL1 NELL2 NOC2L NUP62 PICK1 PNMA1 PPP1R12C PSMC1 RABEP1 RAD23A RNF31 SIAH1 SNX1 SPRY1 SUMO1 SUMO2 TAF10 THY1 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM54 TRRAP TXNDC11 UBQLN2 USP22 VCP VWF
Entrez ID		3913	6314
HPRD ID		01034	06365
Ensembl ID		ENSG00000172037	ENSG00000163635
Uniprot IDs		P55268	O15265 Q9UPD8
PDB IDs			2KKR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?