KRTAP26-1 and COL8A1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KRTAP26-1	COL8A1
Description		keratin associated protein 26-1	collagen type VIII alpha 1 chain
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Extracellular Region Collagen Type VIII Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Keratinization	Angiogenesis Cell Adhesion Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Endodermal Cell Differentiation Camera-type Eye Morphogenesis Epithelial Cell Proliferation
Pathways		Keratinization	Collagen degradation Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Collagen chain trimerization
Drugs
Diseases
GWAS			Advanced age-related macular degeneration ( 26691988) Age-related macular degeneration ( 20385826 23455636) Axial length ( 24144296) Childhood ear infection ( 27182965) Cleft lip with or without cleft palate ( 28054174) Nonsyndromic cleft lip with cleft palate ( 28232668) Optic cup area ( 25631615 31798171 28073927) Optic disc area ( 31798171 28073927) Superior frontal gyrus grey matter volume ( 25335168) Vertical cup-disc ratio ( 31798171 25241763 28073927)
Interacting Genes		28 interacting genes: CCNJL COL8A1 DTX2 GDPD5 GRN HGS HOXA1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-9 KRTAP12-2 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP9-2 MGAT5B NOTCH2NLA OTX1 PSMA3 SF1 STK16 TEKT4 TRIM42 TRIP13 TRIP6	20 interacting genes: ADAMTSL4 COL8A2 CREB5 EFEMP2 INCA1 ITGA1 ITGA2 KLHL12 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP26-1 KRTAP4-12 KRTAP9-2 NOTCH2NLA REL SP4 UBQLN4 VAC14
Entrez ID		388818	1295
HPRD ID		14206	00372
Ensembl ID		ENSG00000197683	ENSG00000144810
Uniprot IDs		Q6PEX3	P27658
PDB IDs
Enriched GO Terms of Interacting Partners?
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