COL8A1 and KRTAP9-2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		COL8A1	KRTAP9-2
Description		collagen type VIII alpha 1 chain	keratin associated protein 9-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type VIII Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix	Cytosol Keratin Filament
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength	Protein Binding Identical Protein Binding
	Biological Process	Angiogenesis Cell Adhesion Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Endodermal Cell Differentiation Camera-type Eye Morphogenesis Epithelial Cell Proliferation	Keratinization
Pathways		Collagen degradation Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Collagen chain trimerization	Keratinization
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Age-related macular degeneration ( 20385826 23455636) Axial length ( 24144296) Childhood ear infection ( 27182965) Cleft lip with or without cleft palate ( 28054174) Nonsyndromic cleft lip with cleft palate ( 28232668) Optic cup area ( 25631615 31798171 28073927) Optic disc area ( 31798171 28073927) Superior frontal gyrus grey matter volume ( 25335168) Vertical cup-disc ratio ( 31798171 25241763 28073927)
Interacting Genes		20 interacting genes: ADAMTSL4 COL8A2 CREB5 EFEMP2 INCA1 ITGA1 ITGA2 KLHL12 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP26-1 KRTAP4-12 KRTAP9-2 NOTCH2NLA REL SP4 UBQLN4 VAC14	54 interacting genes: ADAMTSL4 AQP1 ARFGAP1 CATSPER1 CCDC28A CHRD COL8A1 CREB5 DOCK2 FAM76B GATA1 GLRX3 GNE HOXA1 JOSD1 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-4 LCE1B LCE2A LCE3E LCE4A LNX1 MAPKBP1 MEOX2 NOTCH2NLA NTAQ1 NUFIP2 OTX1 PDE9A PLSCR1 PRKAB2 PTPMT1 RCHY1 RNF31 SHFL SMCP SPATA8 SPRY2 SUMO1P1 TMSB10 ZDHHC17
Entrez ID		1295	83899
HPRD ID		00372	13949
Ensembl ID		ENSG00000144810	ENSG00000239886
Uniprot IDs		P27658	Q9BYQ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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