C12orf75 and ELAVL1

Number of citations of the paper that reports this interaction (PubMedID 29931370)
26

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		C12orf75	ELAVL1
Description		chromosome 12 open reading frame 75	ELAV like RNA binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Cytoplasmic Stress Granule Membrane Postsynapse Glutamatergic Synapse Ribonucleoprotein Complex
	Molecular Function		RNA Binding Double-stranded RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding AU-rich Element Binding Protein Kinase Binding MiRNA Binding MRNA 3'-UTR AU-rich Region Binding Protein Homodimerization Activity
	Biological Process		MRNA Splicing, Via Spliceosome Protein Import Into Nucleus Regulation Of MRNA Stability Positive Regulation Of Translation MRNA Stabilization Protein Homooligomerization Negative Regulation Of Gene Silencing By MiRNA 3'-UTR-mediated MRNA Stabilization Regulation Of Stem Cell Population Maintenance
Pathways			HuR (ELAVL1) binds and stabilizes mRNA mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Alzheimer's disease biomarkers ( 23419831) Carotid plaque burden ( 28282560) Corrected insulin response ( 24699409) Corrected insulin response adjusted for insulin sensitivity index ( 24699409) Mild to moderate chronic kidney disease ( 31178898) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Systolic blood pressure ( 30224653)	Blood protein levels ( 28240269)
Interacting Genes		2 interacting genes: ELAVL1 REL	37 interacting genes: ANP32A ANP32B APOE C12orf75 CARM1 CELF2 CHEK2 CTNNB1 ERG FAF2 GJB3 HNRNPK HOTAIR IL7R KPNA1 KPNB1 MIRLET7B MIRLET7I NOS3 PAIP2 PLAU PLAUR PRKCA PRKCD PRKCE PSEN2 PTBP2 PTGS2 RBFOX2 SDCBP SET SREK1 TNPO1 TNPO2 VCP VEGFA XIAP
Entrez ID		387882	1994
HPRD ID		17368	16025
Ensembl ID		ENSG00000235162	ENSG00000066044
Uniprot IDs		Q8TAD7	Q15717
PDB IDs			3HI9 4ED5 4EGL 4FXV 5SZW 6G2K 6GC5 6GD1 6GD2 6GD3
Enriched GO Terms of Interacting Partners?
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