CCDC184 and PPP1R13B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCDC184	PPP1R13B
Description		coiled-coil domain containing 184	protein phosphatase 1 regulatory subunit 13B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	P53 Binding Protein Binding Transcription Factor Binding
	Biological Process		Regulation Of Apoptotic Process Negative Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Neuron Death Regulation Of Signal Transduction By P53 Class Mediator
Pathways			Activation of PUMA and translocation to mitochondria TP53 Regulates Transcription of Genes Involved in Cytochrome C Release TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain TP53 Regulates Transcription of Death Receptors and Ligands Regulation of TP53 Activity through Association with Co-factors
Drugs
Diseases
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bitter alcoholic beverage consumption ( 31046077) Body mass index ( 26426971) General risk tolerance (MTAG) ( 30643258) Schizophrenia ( 25056061 29483656) Triglycerides ( 30275531)
Interacting Genes		8 interacting genes: GPANK1 NTAQ1 PBLD PIN1 PPP1R13B RPL9 STX11 TRAF5	14 interacting genes: APC BRCA1 CCDC184 CDC5L CEP63 KHDRBS1 KHDRBS3 MIPOL1 PLEKHA5 PPP1CA TNIK TP63 TP73 TRAF1
Entrez ID		387856	23368
HPRD ID		18375	07345
Ensembl ID		ENSG00000177875	ENSG00000088808
Uniprot IDs		Q52MB2	Q96KQ4
PDB IDs			6HL5
Enriched GO Terms of Interacting Partners?
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