PPP1R13B and MIPOL1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PPP1R13B	MIPOL1
Description		protein phosphatase 1 regulatory subunit 13B	mirror-image polydactyly 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm	Nucleus
	Molecular Function	P53 Binding Protein Binding Transcription Factor Binding	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Apoptotic Process Negative Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Neuron Death Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Activation of PUMA and translocation to mitochondria TP53 Regulates Transcription of Genes Involved in Cytochrome C Release TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain TP53 Regulates Transcription of Death Receptors and Ligands Regulation of TP53 Activity through Association with Co-factors
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bitter alcoholic beverage consumption ( 31046077) Body mass index ( 26426971) General risk tolerance (MTAG) ( 30643258) Schizophrenia ( 25056061 29483656) Triglycerides ( 30275531)	Estimated glomerular filtration rate ( 31152163) Intraocular pressure ( 29617998) Longitudinal alcohol consumption ( 26081443) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Tonsillectomy ( 27182965 28928442)
Interacting Genes		14 interacting genes: APC BRCA1 CCDC184 CDC5L CEP63 KHDRBS1 KHDRBS3 MIPOL1 PLEKHA5 PPP1CA TNIK TP63 TP73 TRAF1	38 interacting genes: ARNT2 ATP5PO BEX2 BYSL CCDC33 CCT3 CDK18 CKS1B DGCR6 EAF1 EIF4E2 ENKD1 FAM161A FBF1 HAUS1 MAGEA6 MCM7 MFAP1 MYLIP NEBL PPP1R13B PRPF31 RBM41 RCOR3 RNF6 RPL10L RTP5 SCNM1 SMARCE1 SRPK2 SSX3 TCHP TTC12 UBE2K USH1C UTP25 ZGPAT ZNF688
Entrez ID		23368	145282
HPRD ID		07345	06029
Ensembl ID		ENSG00000088808	ENSG00000151338
Uniprot IDs		Q96KQ4	A8K735 G5EA54 Q4G0U7 Q8TD10
PDB IDs		6HL5
Enriched GO Terms of Interacting Partners?
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