PPP1R13B and KHDRBS3

Number of citations of the paper that reports this interaction (PubMedID 16474851)
8

Data Source:
BioGRID (far western blotting)

		PPP1R13B	KHDRBS3
Description		protein phosphatase 1 regulatory subunit 13B	KH RNA binding domain containing, signal transduction associated 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	P53 Binding Protein Binding Transcription Factor Binding	RNA Binding Protein Binding SH3 Domain Binding Protein Domain Specific Binding Identical Protein Binding
	Biological Process	Regulation Of Apoptotic Process Negative Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Neuron Death Regulation Of Signal Transduction By P53 Class Mediator	MRNA Processing Viral Process Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Activation of PUMA and translocation to mitochondria TP53 Regulates Transcription of Genes Involved in Cytochrome C Release TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain TP53 Regulates Transcription of Death Receptors and Ligands Regulation of TP53 Activity through Association with Co-factors	PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bitter alcoholic beverage consumption ( 31046077) Body mass index ( 26426971) General risk tolerance (MTAG) ( 30643258) Schizophrenia ( 25056061 29483656) Triglycerides ( 30275531)	Chronotype ( 30696823) Disease progression in age-related macular degeneration ( 29346644) Polycystic ovary syndrome ( 25574032) Squamous cell lung carcinoma ( 28604730) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		14 interacting genes: APC BRCA1 CCDC184 CDC5L CEP63 KHDRBS1 KHDRBS3 MIPOL1 PLEKHA5 PPP1CA TNIK TP63 TP73 TRAF1	33 interacting genes: BAHD1 CACNA1A CCDC33 DMRT3 FBXO7 FUS HNRNPC HNRNPK INPP5D KHDRBS1 KHDRBS2 LNX1 MARK4 NCOA5 NELFB NUDT18 PPP1R13B PRMT1 PRPF31 PSMF1 PTBP2 RBBP6 RBM7 RBMX RBMY1A1 SGSM2 SIAH1 SNRPC SRSF9 U2AF2 YTHDC1 ZNF408 ZNF688
Entrez ID		23368	10656
HPRD ID		07345	10007
Ensembl ID		ENSG00000088808	ENSG00000131773
Uniprot IDs		Q96KQ4	O75525
PDB IDs		6HL5	5EL3 5ELR 5ELS 5ELT 5EMO
Enriched GO Terms of Interacting Partners?
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