SUMO4 and ENO1

Number of citations of the paper that reports this interaction (PubMedID 16236267)
27

Data Source:
HPRD (in vivo)

		SUMO4	ENO1
Description		small ubiquitin like modifier 4	enolase 1
Image		No pdb structure
GO Annotations	Cellular Component		Phosphopyruvate Hydratase Complex Extracellular Space Nucleus Cytoplasm Cytosol Plasma Membrane Cell Surface Membrane M Band Extracellular Exosome Cell Cortex Region
	Molecular Function		Magnesium Ion Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Binding Phosphopyruvate Hydratase Activity Protein Binding Protein Homodimerization Activity Cadherin Binding GTPase Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Gluconeogenesis Response To Virus Positive Regulation Of Plasminogen Activation Negative Regulation Of Cell Growth Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Muscle Contraction Canonical Glycolysis Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of ATP Biosynthetic Process
Pathways			Glycolysis Gluconeogenesis Manipulation of host energy metabolism
Drugs			Zinc Copper Artenimol
Diseases
GWAS		Dupuytren's disease ( 28886342)	Asthma ( 30929738) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Blood protein levels ( 30072576) Feeling tense ( 29500382) Plateletcrit ( 27863252) Tonsillectomy ( 27182965 28928442) White blood cell count (basophil) ( 27863252)
Interacting Genes		75 interacting genes: ACADM ACO2 ACTG1 ALDOA ARHGDIA ATP5F1B CALR CAT CCT2 CCT5 CCT6A CCT7 CLIC1 DNAJA1 DNAJB11 EIF3I ENO1 ENO2 FOS G6PD GAPDH GMPS GSTP1 HNRNPD HNRNPF HNRNPH1 HNRNPL HSPA1B HSPA5 HSPA8 HSPA9 HSPD1 IDH1 IDH3A IMPDH2 JUN LDHB LMNA LMNB1 MRPS22 NFKBIA NR3C1 PA2G4 PAFAH1B3 PDIA3 PDIA6 PGK1 PHB PHGDH PITHD1 PPA1 PRDX2 PRDX3 PRDX4 PRDX6 PRPS1 PSMC2 RACK1 RPSA SF3B4 SPINT2 STAT1 STAT3 STIP1 STOML2 STRAP TFAP2A TOP2A TPM3 TUBA1C TXNL1 UBE2V1 VCP VDAC1 ZPR1	26 interacting genes: AGTPBP1 AMBP BHLHE40 BRCA1 CHEK2 CLK1 FANCA FYN GRB2 HDAC1 HEMGN HSPB2 LIG4 MCPH1 MYOC PCNA PLG SERPING1 SRC SUMO2 SUMO4 TERT TRAPPC2 UPF2 YWHAQ YWHAZ
Entrez ID		387082	2023
HPRD ID		10584	01400
Ensembl ID		ENSG00000177688	ENSG00000074800
Uniprot IDs		Q6EEV6	A0A024R4F1 P06733
PDB IDs			2PSN 3B97 5JLZ 5LAX 5NI9 5NIG 5OCK
Enriched GO Terms of Interacting Partners?
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