KCNJ4 and IL16

Number of citations of the paper that reports this interaction (PubMedID 10479680)
20

Data Source:
HPRD (two hybrid)

		KCNJ4	IL16
Description		potassium inwardly rectifying channel subfamily J member 4	interleukin 16
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GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Basolateral Plasma Membrane Cell Junction Cytoplasmic Vesicle Membrane Postsynaptic Membrane	Extracellular Region Extracellular Space Cytosol Plasma Membrane Nuclear Speck Flemming Body
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding PDZ Domain Binding	Cytokine Activity CD4 Receptor Binding
	Biological Process	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Cardiac Conduction Potassium Ion Import Across Plasma Membrane	Immune Response Viral Process Cytokine-mediated Signaling Pathway Leukocyte Chemotaxis Induction Of Positive Chemotaxis Regulation Of Calcium Ion Transport
Pathways		Activation of G protein gated Potassium channels Classical Kir channels Phase 4 - resting membrane potential Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Other interleukin signaling
Drugs		Carvedilol
Diseases
GWAS		Automobile speeding propensity ( 30643258) Chronotype ( 30696823) Conotruncal heart defects ( 24800985)	Blood protein levels ( 30072576 29875488 28240269) Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Brown vs. black hair color ( 30531825) Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Height ( 31562340) Inattentive symptoms ( 18821565) Interleukin-16 levels ( 27989323) Primary biliary cholangitis ( 28425483)
Interacting Genes		10 interacting genes: CASK DLG1 DLG2 DLG4 GNGT2 IL16 KCNJ2 LIN7B PRKCD SNTA1	31 interacting genes: CASP3 CD4 CDK1 CSNK2A1 CSNK2A2 DMRTB1 EFEMP2 GABPB1 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 KCNA3 KCND1 KCND2 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KDM1A LNX2 PCSK6 PPP1R12A PPP1R12B PPP1R12C SUV39H1 TFIP11 TRIP6 USHBP1 ZNRD2
Entrez ID		3761	3603
HPRD ID		02738	04329
Ensembl ID		ENSG00000168135	ENSG00000172349
Uniprot IDs		A0A024R1L8 P48050 Q58F07	Q14005 Q9UME6
PDB IDs		3GJ9	1I16 1X6D 5FB8
Enriched GO Terms of Interacting Partners?
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